Iain Mattaj

Publications

• Yokoyama H, Nakos K, Santarella-Mellwig R, Rybina S, Krijgsveld J, Koffa MD, Mattaj IW. (2013) CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation Curr. Biol. 23(24):2443-2451. doi: 10.1016/j.cub.2013.09.062 Europe PMC | doi Dekker J, Wysocka J, Mattaj I, Lieberman Aiden E, Pikaard C. (2013) Nuclear biology: what's been most surprising? Cell 152(6):1207-1208. doi: 10.1016/j.cell.2013.02.041 Europe PMC | doi Santarella-Mellwig R, Pruggnaller S, Roos N, Mattaj IW, Devos DP. (2013) Three-dimensional reconstruction of bacteria with a complex endomembrane system PLoS Biol. 11(5):e1001565. doi: 10.1371/journal.pbio.1001565 Europe PMC | doi 2012 Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW. (2012) Mitotic lamin disassembly is triggered by lipid-mediated signaling J. Cell Biol. 198(6):981-990. doi: 10.1083/jcb.201205103 Europe PMC | doi Tooze J, Mattaj I, Rorth P, Pulverer B. (2012) Evolution and revolution at The EMBO Journal EMBO J 31(15):3231-3233. doi: 10.1038/emboj.2012.208 doi Asencio C, Davidson IF, Santarella-Mellwig R, Ly-Hartig TB, Mall M, Wallenfang MR, Mattaj IW, Gorjánácz M. (2012) Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis Cell 150(1):122-135. doi: 10.1016/j.cell.2012.04.043 Europe PMC | doi Borrego-Pinto J, Jegou T, Osorio DS, Auradé F, Gorjánácz M, Koch B, Mattaj IW, Gomes ER. (2012) Samp1 is a component of TAN lines and is required for nuclear movement J. Cell. Sci. 125(Pt 5):1099-1105. doi: 10.1242/jcs.087049 Europe PMC | doi 2011 Symens N, Walczak R, Demeester J, Mattaj I, De Smedt SC, Remaut K. (2011) Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles Mol. Pharm. 8(5):1757-1766. doi: 10.1021/mp200120v Europe PMC | doi Simons K, Mattaj IW. (2011) Retrospective. Lennart Philipson (1929-2011) Science 333(6043):711. doi: 10.1126/science.1210990 Europe PMC | doi 2010 Mattaj IW. (2010) It's the Technology, Stupid Mol. Biol. Cell 21(22):3805-3806. doi: 10.1091/mbc.e10-04-0342 Europe PMC | doi Mattaj IW, Müller CW. (2010) Solving the NES problem Nat. Struct. Mol. Biol. 17(11):1288-1289. doi: 10.1038/nsmb1110-1288 Europe PMC | doi Yavuz S, Santarella-Mellwig R, Koch B, Jaedicke A, Mattaj IW, Antonin W. (2010) NLS-mediated NPC functions of the nucleoporin Pom121 FEBS Lett. 584(15):3292-3298. doi: 10.1016/j.febslet.2010.07.008 Europe PMC | doi Mattaj IW. (2010) Coordinated action needed for Europe's research programmes Nature 465(7301):1005. doi: 10.1038/4651005a Europe PMC | doi Santarella-Mellwig R, Franke J, Jaedicke A, Gorjanacz M, Bauer U, Budd A, Mattaj IW, Devos DP. (2010) The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins PLoS Biol. 8(1):e1000281. doi: 10.1371/journal.pbio.1000281 Europe PMC | doi 2009 Platani M, Santarella-Mellwig R, Posch M, Walczak R, Swedlow JR, Mattaj IW. (2009) The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex Mol. Biol. Cell 20(24):5260-5275. doi: 10.1091/mbc.e09-05-0377 Europe PMC | doi Yokoyama H, Rybina S, Santarella-Mellwig R, Mattaj IW, Karsenti E. (2009) ISWI is a RanGTP-dependent MAP required for chromosome segregation J. Cell Biol. 187(6):813-829. doi: 10.1083/jcb.200906020 Europe PMC | doi Gorjánácz M, Mattaj IW. (2009) Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans J. Cell. Sci. 122(Pt 12):1963-1969. doi: 10.1242/jcs.044750 Europe PMC | doi 2008 Casanova CM, Rybina S, Yokoyama H, Karsenti E, Mattaj IW. (2008) Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2 Mol. Biol. Cell 19(11):4900-4908. doi: 10.1091/mbc.e08-06-0624 Europe PMC | doi Hawryluk-Gara LA, Platani M, Santarella R, Wozniak RW, Mattaj IW. (2008) Nup53 is required for nuclear envelope and nuclear pore complex assembly Mol. Biol. Cell 19(4):1753-1762. doi: 10.1091/mbc.e07-08-0820 Europe PMC | doi Yokoyama H, Gruss OJ, Rybina S, Caudron M, Schelder M, Wilm M, Mattaj IW, Karsenti E. (2008) Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate J. Cell Biol. 180(5):867-875. doi: 10.1083/jcb.200706189 Europe PMC | doi Galy V, Antonin W, Jaedicke A, Sachse M, Santarella R, Haselmann U, Mattaj I. (2008) A role for gp210 in mitotic nuclear-envelope breakdown J. Cell. Sci. 121(Pt 3):317-328. doi: 10.1242/jcs.022525 Europe PMC | doi Cohen M, Santarella R, Wiesel N, Mattaj I, Gruenbaum Y. (2008) Electron microscopy of lamin and the nuclear lamina in Caenorhabditis elegans Methods Cell Biol. 88:411-429. doi: 10.1016/s0091-679x(08)00421-4 Europe PMC | doi Kitao S, Segref A, Kast J, Wilm M, Mattaj IW, Ohno M. (2008) A compartmentalized phosphorylation/dephosphorylation system that regulates U snRNA export from the nucleus Mol. Cell. Biol. 28(1):487-497. doi: 10.1128/mcb.01189-07 Europe PMC | doi Mattaj I. (2008) Comments from the European Molecular Biology Laboratory Dis Model Mech 1(1):16. doi: 10.1242/dmm.000794 Europe PMC | doi 2007 Arai K, Cech T, Chameau JL, Horn P, Mattaj I, Potocnik J, Wiley J. (2007) The future of research universities. Is the model of research-intensive universities still valid at the beginning of the twenty-first century? EMBO Rep. 8(9):804-810. doi: 10.1038/sj.embor.7401052 Europe PMC | doi Fortes P, Longman D, McCracken S, Ip JY, Poot R, Mattaj IW, Cáceres JF, Blencowe BJ. (2007) Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation FEBS Lett. 581(16):3087-3097. doi: 10.1016/j.febslet.2007.05.066 Europe PMC | doi Gorjánácz M, Jaedicke A, Mattaj IW. (2007) What can Caenorhabditis elegans tell us about the nuclear envelope? FEBS Lett. 581(15):2794-2801. doi: 10.1016/j.febslet.2007.03.052 Europe PMC | doi Mattaj IW, Tocchini-Valentini GP. (2007) Laying solid foundations for Europe Nature 447(7143):377-378. doi: 10.1038/447377a Europe PMC | doi Franz C, Walczak R, Yavuz S, Santarella R, Gentzel M, Askjaer P, Galy V, Hetzer M, Mattaj IW, Antonin W. (2007) MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly EMBO Rep. 8(2):165-172. doi: 10.1038/sj.embor.7400889 Europe PMC | doi Ribbeck K, Raemaekers T, Carmeliet G, Mattaj IW. (2007) A role for NuSAP in linking microtubules to mitotic chromosomes Curr. Biol. 17(3):230-236. doi: 10.1016/j.cub.2006.11.050 Europe PMC | doi Gorjánácz M, Klerkx EP, Galy V, Santarella R, López-Iglesias C, Askjaer P, Mattaj IW. (2007) Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly EMBO J. 26(1):132-143. doi: 10.1038/sj.emboj.7601470 Europe PMC | doi Gorjánácz M, Mattaj IW, Rietdorf J. (2007) Some Like It Hot Imaging & Microscopy 9(1):28-29. Europe PMC 2006 Ulbert S, Antonin W, Platani M, Mattaj IW. (2006) The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology FEBS Lett. 580(27):6435-6441. doi: 10.1016/j.febslet.2006.10.060 Europe PMC | doi Galy V, Askjaer P, Franz C, López-Iglesias C, Mattaj IW. (2006) MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegans Curr. Biol. 16(17):1748-1756. doi: 10.1016/j.cub.2006.06.067 Europe PMC | doi Ribbeck K, Groen AC, Santarella R, Bohnsack MT, Raemaekers T, Köcher T, Gentzel M, Görlich D, Wilm M, Carmeliet G, Mitchison TJ, Ellenberg J, Hoenger A, Mattaj IW. (2006) NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules Mol. Biol. Cell 17(6):2646-2660. doi: 10.1091/mbc.e05-12-1178 Europe PMC | doi Ulbert S, Platani M, Boue S, Mattaj IW. (2006) Direct membrane protein-DNA interactions required early in nuclear envelope assembly J. Cell Biol. 173(4):469-476. doi: 10.1083/jcb.200512078 Europe PMC | doi Koffa MD, Casanova CM, Santarella R, Köcher T, Wilm M, Mattaj IW. (2006) HURP is part of a Ran-dependent complex involved in spindle formation Curr. Biol. 16(8):743-754. doi: 10.1016/j.cub.2006.03.056 Europe PMC | doi Mansfeld J, Güttinger S, Hawryluk-Gara LA, Panté N, Mall M, Galy V, Haselmann U, Mühlhäusser P, Wozniak RW, Mattaj IW, Kutay U, Antonin W. (2006) The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells Mol. Cell 22(1):93-103. doi: 10.1016/j.molcel.2006.02.015 Europe PMC | doi Czaplinski K, Mattaj IW. (2006) 40LoVe interacts with Vg1RBP/Vera and hnRNP I in binding the Vg1-localization element RNA 12(2):213-222. doi: 10.1261/rna.2820106 Europe PMC | doi Schetter A, Askjaer P, Piano F, Mattaj I, Kemphues K. (2006) Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans Dev. Biol. 289(2):360-371. doi: 10.1016/j.ydbio.2005.10.038 Europe PMC | doi 2005 Franz C, Askjaer P, Antonin W, Iglesias CL, Haselmann U, Schelder M, de Marco A, Wilm M, Antony C, Mattaj IW. (2005) Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates EMBO J. 24(20):3519-3531. doi: 10.1038/sj.emboj.7600825 Europe PMC | doi Mattaj I. (2005) EMBL's fourth decade EMBO Rep. 6(10):904-907. doi: 10.1038/sj.embor.7400546 Europe PMC | doi Czaplinski K, Köcher T, Schelder M, Segref A, Wilm M, Mattaj IW. (2005) Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis Dev. Cell 8(4):505-515. doi: 10.1016/j.devcel.2005.01.012 Europe PMC | doi Becskei A, Mattaj IW. (2005) Quantitative models of nuclear transport Curr. Opin. Cell Biol. 17(1):27-34. doi: 10.1016/j.ceb.2004.12.010 Europe PMC | doi Antonin W, Franz C, Haselmann U, Antony C, Mattaj IW. (2005) The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation Mol. Cell 17(1):83-92. doi: 10.1016/j.molcel.2004.12.010 Europe PMC | doi Antonin W, Mattaj IW. (2005) Nuclear pore complexes: round the bend? Nat. Cell Biol. 7(1):10-12. doi: 10.1038/ncb0105-10 Europe PMC | doi Hetzer MW, Walther TC, Mattaj IW. (2005) Pushing the envelope: structure, function, and dynamics of the nuclear periphery Annu. Rev. Cell Dev. Biol. 21:347-380. doi: 10.1146/annurev.cellbio.21.090704.151152 Europe PMC | doi 2004 Petosa C, Schoehn G, Askjaer P, Bauer U, Moulin M, Steuerwald U, Soler-López M, Baudin F, Mattaj IW, Müller CW. (2004) Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex Mol. Cell 16(5):761-775. doi: 10.1016/j.molcel.2004.11.018 Europe PMC | doi Yamada M, Mattaj IW, Yoneda Y. (2004) An ATP-dependent activity that releases RanGDP from NTF2 J. Biol. Chem. 279(35):36228-36234. doi: 10.1074/jbc.m403101200 Europe PMC | doi Hachet V, Köcher T, Wilm M, Mattaj IW. (2004) Importin alpha associates with membranes and participates in nuclear envelope assembly in vitro EMBO J. 23(7):1526-1535. doi: 10.1038/sj.emboj.7600154 Europe PMC | doi Mattaj IW. (2004) Sorting out the nuclear envelope from the endoplasmic reticulum Nat. Rev. Mol. Cell Biol. 5(1):65-69. doi: 10.1038/nrm1263 Europe PMC | doi 2003 Galy V, Mattaj IW, Askjaer P. (2003) Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo Mol. Biol. Cell 14(12):5104-5115. doi: 10.1091/mbc.e03-04-0237 Europe PMC | doi Walther TC, Askjaer P, Gentzel M, Habermann A, Griffiths G, Wilm M, Mattaj IW, Hetzer M. (2003) RanGTP mediates nuclear pore complex assembly Nature 424(6949):689-694. doi: 10.1038/nature01898 Europe PMC | doi Schatz CA, Santarella R, Hoenger A, Karsenti E, Mattaj IW, Gruss OJ, Carazo-Salas RE. (2003) Importin alpha-regulated nucleation of microtubules by TPX2 EMBO J. 22(9):2060-2070. doi: 10.1093/emboj/cdg195 Europe PMC | doi Walther TC, Alves A, Pickersgill H, Loïodice I, Hetzer M, Galy V, Hülsmann BB, Köcher T, Wilm M, Allen T, Mattaj IW, Doye V. (2003) The conserved Nup107-160 complex is critical for nuclear pore complex assembly Cell 113(2):195-206. doi: 10.1016/s0092-8674(03)00235-6 Europe PMC | doi Becskei A, Mattaj IW. (2003) The strategy for coupling the RanGTP gradient to nuclear protein export Proc. Natl. Acad. Sci. U.S.A. 100(4):1717-1722. doi: 10.1073/pnas.252766999 Europe PMC | doi 2002 Askjaer P, Galy V, Hannak E, Mattaj IW. (2002) Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos Mol. Biol. Cell 13(12):4355-4370. doi: 10.1091/mbc.e02-06-0346 Europe PMC | doi Mazza C, Segref A, Mattaj IW, Cusack S. (2002) Co-crystallization of the human nuclear cap-binding complex with a m7GpppG cap analogue using protein engineering Acta Crystallogr. D Biol. Crystallogr. 58(Pt 12):2194-2197. doi: 10.1107/s0907444902015445 Europe PMC | doi Gruss OJ, Wittmann M, Yokoyama H, Pepperkok R, Kufer T, Silljé H, Karsenti E, Mattaj IW, Vernos I. (2002) Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells Nat. Cell Biol. 4(11):871-879. doi: 10.1038/ncb870 Europe PMC | doi Mazza C, Segref A, Mattaj IW, Cusack S. (2002) Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex EMBO J. 21(20):5548-5557. doi: 10.1093/emboj/cdf538 Europe PMC | doi Massenet S, Pellizzoni L, Paushkin S, Mattaj IW, Dreyfuss G. (2002) The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway Mol. Cell. Biol. 22(18):6533-6541. doi: 10.1128/mcb.22.18.6533-6541.2002 Europe PMC | doi Kuersten S, Arts GJ, Walther TC, Englmeier L, Mattaj IW. (2002) Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains Mol. Cell. Biol. 22(16):5708-5720. doi: 10.1128/mcb.22.16.5708-5720.2002 Europe PMC | doi Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW. (2002) Ran binds to chromatin by two distinct mechanisms Curr. Biol. 12(13):1151-1156. doi: 10.1016/s0960-9822(02)00927-2 Europe PMC | doi Hetzer M, Gruss OJ, Mattaj IW. (2002) The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly Nat. Cell Biol. 4(7):E177-84. doi: 10.1038/ncb0702-e177 Europe PMC | doi Walther TC, Pickersgill HS, Cordes VC, Goldberg MW, Allen TD, Mattaj IW, Fornerod M. (2002) The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import J. Cell Biol. 158(1):63-77. doi: 10.1083/jcb.200202088 Europe PMC | doi Ohno M, Segref A, Kuersten S, Mattaj IW. (2002) Identity elements used in export of mRNAs Mol. Cell 9(3):659-671. doi: 10.1016/s1097-2765(02)00454-9 Europe PMC | doi 2001 Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW. (2001) Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly Nat. Cell Biol. 3(12):1086-1091. doi: 10.1038/ncb1201-1086 Europe PMC | doi Kuersten S, Ohno M, Mattaj IW. (2001) Nucleocytoplasmic transport: Ran, beta and beyond Trends Cell Biol. 11(12):497-503. doi: 10.1016/s0962-8924(01)02144-4 Europe PMC | doi Englmeier L, Fornerod M, Bischoff FR, Petosa C, Mattaj IW, Kutay U. (2001) RanBP3 influences interactions between CRM1 and its nuclear protein export substrates EMBO Rep. 2(10):926-932. doi: 10.1093/embo-reports/kve200 Europe PMC | doi Koffa MD, Clements JB, Izaurralde E, Wadd S, Wilson SA, Mattaj IW, Kuersten S. (2001) Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway EMBO J. 20(20):5769-5778. doi: 10.1093/emboj/20.20.5769 Europe PMC | doi Walther TC, Fornerod M, Pickersgill H, Goldberg M, Allen TD, Mattaj IW. (2001) The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins EMBO J. 20(20):5703-5714. doi: 10.1093/emboj/20.20.5703 Europe PMC | doi Mazza C, Ohno M, Segref A, Mattaj IW, Cusack S. (2001) Crystal structure of the human nuclear cap binding complex Mol. Cell 8(2):383-396. doi: 10.1016/s1097-2765(01)00299-4 Europe PMC | doi Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E. (2001) Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly Nat. Cell Biol. 3(3):228-234. doi: 10.1038/35060009 Europe PMC | doi Segref A, Mattaj IW, Ohno M. (2001) The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export RNA 7(3):351-360. doi: 10.1017/s1355838201002278 Europe PMC | doi Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW. (2001) Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity Cell 104(1):83-93. doi: 10.1016/s0092-8674(01)00193-3 Europe PMC | doi 2000 Fortes P, Inada T, Preiss T, Hentze MW, Mattaj IW, Sachs AB. (2000) The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation Mol. Cell 6(1):191-196. doi: 10.1016/s1097-2765(00)00020-4 Europe PMC | doi Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW. (2000) GTP hydrolysis by Ran is required for nuclear envelope assembly Mol. Cell 5(6):1013-1024. doi: 10.1016/s1097-2765(00)80266-x Europe PMC | doi Ohno M, Segref A, Bachi A, Wilm M, Mattaj IW. (2000) PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation Cell 101(2):187-198. doi: 10.1016/s0092-8674(00)80829-6 Europe PMC | doi Varani L, Gunderson SI, Mattaj IW, Kay LE, Neuhaus D, Varani G. (2000) The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein Nat. Struct. Biol. 7(4):329-335. doi: 10.1038/74101 Europe PMC | doi Vagner S, Rüegsegger U, Gunderson SI, Keller W, Mattaj IW. (2000) Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP RNA 6(2):178-188. doi: 10.1017/s1355838200991854 Europe PMC | doi Vagner S, Vagner C, Mattaj IW. (2000) The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing Genes Dev. 14(4):403-413. Europe PMC Hetzer M, Mattaj IW. (2000) An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins J. Cell Biol. 148(2):293-303. doi: 10.1083/jcb.148.2.293 Europe PMC | doi 1999 Fortes P, Kufel J, Fornerod M, Polycarpou-Schwarz M, Lafontaine D, Tollervey D, Mattaj IW. (1999) Genetic and physical interactions involving the yeast nuclear cap-binding complex Mol. Cell. Biol. 19(10):6543-6553. Europe PMC Askjaer P, Bachi A, Wilm M, Bischoff FR, Weeks DL, Ogniewski V, Ohno M, Niehrs C, Kjems J, Mattaj IW, Fornerod M. (1999) RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase Mol. Cell. Biol. 19(9):6276-6285. Europe PMC Fortes P, Bilbao-Cortés D, Fornerod M, Rigaut G, Raymond W, Séraphin B, Mattaj IW. (1999) Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition Genes Dev. 13(18):2425-2438. doi: 10.1101/gad.13.18.2425 Europe PMC | doi Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW. (1999) Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation Nature 400(6740):178-181. doi: 10.1038/22133 Europe PMC | doi Mattaj IW, Conti E. (1999) Cell biology. Snail mail to the nucleus Nature 399(6733):208-210. doi: 10.1038/20322 Europe PMC | doi Ségault V, Will CL, Polycarpou-Schwarz M, Mattaj IW, Branlant C, Lührmann R. (1999) Conserved loop I of U5 small nuclear RNA is dispensable for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts Mol. Cell. Biol. 19(4):2782-2790. Europe PMC Wilson KF, Fortes P, Singh US, Ohno M, Mattaj IW, Cerione RA. (1999) The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction J. Biol. Chem. 274(7):4166-4173. doi: 10.1074/jbc.274.7.4166 Europe PMC | doi Englmeier L, Olivo JC, Mattaj IW. (1999) Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis Curr. Biol. 9(1):30-41. doi: 10.1016/s0960-9822(99)80044-x Europe PMC | doi Ohno M, Mattaj IW. (1999) Meiosis: MeiRNA hits the spot Curr. Biol. 9(2):R66-9. doi: 10.1016/s0960-9822(99)80013-x Europe PMC | doi 1998 Arts GJ, Kuersten S, Romby P, Ehresmann B, Mattaj IW. (1998) The role of exportin-t in selective nuclear export of mature tRNAs EMBO J. 17(24):7430-7441. doi: 10.1093/emboj/17.24.7430 Europe PMC | doi Arts GJ, Fornerod M, Mattaj IW. (1998) Identification of a nuclear export receptor for tRNA Curr. Biol. 8(6):305-314. doi: 10.1016/s0960-9822(98)70130-7 Europe PMC | doi Ohno M, Fornerod M, Mattaj IW. (1998) Nucleocytoplasmic transport: the last 200 nanometers Cell 92(3):327-336. doi: 10.1016/s0092-8674(00)80926-5 Europe PMC | doi Gunderson SI, Polycarpou-Schwarz M, Mattaj IW. (1998) U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase Mol. Cell 1(2):255-264. doi: 10.1016/s1097-2765(00)80026-x Europe PMC | doi Mattaj IW. (1998) Ribonucleoprotein assembly: clues from spinal muscular atrophy Curr. Biol. 8(3):R93-5. doi: 10.1016/s0960-9822(98)70055-7 Europe PMC | doi Mattaj IW, Englmeier L. (1998) Nucleocytoplasmic transport: the soluble phase Annu. Rev. Biochem. 67:265-306. doi: 10.1146/annurev.biochem.67.1.265 Europe PMC | doi 1997 Izaurralde E, Kutay U, von Kobbe C, Mattaj IW, Görlich D. (1997) The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus EMBO J. 16(21):6535-6547. doi: 10.1093/emboj/16.21.6535 Europe PMC | doi 1 2 3Next

• Yokoyama H, Koch B, Walczak R, Ciray-Duygu F, González-Sánchez JC, Devos DP, Mattaj IW, Gruss OJ. (2014) The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation. Nat Commun 5:3270. doi: 10.1038/ncomms4270

• Christodoulou A, Santarella-Mellwig R, Santama N, Mattaj IW. (2016) Transmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells. J. Cell. Sci. 129(8):1552-65-1565. doi: 10.1242/jcs.175273

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