Alexander Weng
Professor
Department of Pharmacy
Federal Institute for Risk Assessment
Germany
Biography
Alexander Weng is a professor of pharmacy in Federal University for Risk.
Research Interest
Isolation and characterization of natural products with special focus on triterpene saponins and ribosome-inactivating proteins, Development of siRNA and DNA nanocarriers, Tools to improve the endosomal escape process and Targeted toxins (immunotoxins)
Publications
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Thakur M, Jerz G, Tuwalska D, Gilabert-Oriol R, Wybraniec S, Winterhalter P, et al. (2014). High-speed countercurrent chromatographic recovery and off-line electrospray ionization mass spectrometry profiling of bisdesmodic saponins from Saponaria officinalis possessing synergistic toxicity enhancing properties on targeted antitumor toxins. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 955-956: 1-9
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Holmes SE, Bachran C, Fuchs H, Weng A, Melzig MF, Flavell SU, et al. (2015). Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukemia and lymphoma cells is partially immunospecific and target molecule dependent. Immunopharmacology and immunotoxicology 37: 42-55.
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Weng A, Manunta MD, Thakur M, Gilabert-Oriol R, Tagalakis AD, Eddaoudi A, et al. (2015). Improved intracellular delivery of peptide- and lipid-nanoplexes by natural glycosides. Journal of Controlled Release Society.