Gerhard Wolber
Professor
Department of Pharmacy
Federal Institute for Risk Assessment
Germany
Biography
Gerhard Wolber ia a professor in Institute of Pharmacology in Federal University for Risk.
Research Interest
Molecular Modeling & Cheminformatics, Structural and ligand-based drug design, 3D Pharmacophores, Molecular dynamics simulations, Development of methods for the implementation and improvement of virtual screening
Publications
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M. S. Murgueitio, C. Rakers, A. Frank, and G. Wolber. Balancing Inflammation: Computational Design of Small-Molecule Toll-like Receptor Modulators, Trends Pharmacol Sci, 38(2):155-168, 2017. Links: [doi:10.1016/j.tips.2016.10.007] [Publisher]
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M. S. Murgueitio, S. Ebner, P. Hörtnagl, C. Rakers, R. Bruckner, P. Henneke, G. Wolber, and S. S. Sierra. Enhanced immunostimulatory activity of in silico discovered agonists of Toll-like receptor 2 (TLR2), Biochimica et Biophysica Acta (BBA) - General Subjects, :e-pub ahead of print, 2017. Links: [doi:10.1016/j.bbagen.2017.07.011] [Publisher]
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M. Bermudez, A. Bock, F. Krebs, U. Holzgrabe, K. Mohr, M. J. Lohse, and G. Wolber. Ligand-specific restriction of extracellular conformational dynamics constrains signaling of the M2 muscarinic receptor, ACS Medicinal Chemistry Letters, 12(7):1743–1748, 2017. Links: [doi:10.1021/acschembio.7b00275] [Publisher]
