Alexander Gottschalk
Biophysical Chemistry
Frankfurt University
Germany
Biography
Prof. Dr. Alexander Gottschalk Born on August 1969. Education:1990 - 1995 Studies in chemistry, biochemistry and immunology, Johann Wolfgang Goethe University, Frankfurt (Germany), Philipps University, Marburg (Germany) and University of Edinburgh, Edinburgh (Scotland) 1995 - 1999 Diploma & PhD theses (Dr. rer. nat.): Purification and characterization of small nuclear ribonucleoprotein complexes (UsnRPs) from S. cerevisiae with Prof. Dr. Reinhard Lührmann at Unversity of Marburg (Germany) 2000 - 2003 Postdoctoral fellow in the lab of Prof. Dr. William R. Schafer: Adaptation of the Caenorhabditis elegans nervous system to nicotine and proeomics of nicotinic acetylcholine receptors (nAChRs) at the University of California, San Diego (USA) 2004-2009 Juniorprofessor for Molecular Membrane Biology, Independent research group leader at the Johann Wolfgang Goethe University, Frankfurt (Germany) since 2010 Heisenberg-Professor for Molecular Cell Biology and Neurobiochemistry
Research Interest
Membrane Biology Neurobiology
Publications
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Glock C, Nagpal J, Gottschalk A (2015) Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior. In: C. elegans: Methods and Applications, Methods in Molecular Biology (Biron D, Haspel G, eds.), vol. 1327
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Schüler C*, Fischer E*, Shaltiel L, Steuer Costa W, Gottschalk A. (2015) Arrhythmogenic effects of mutated L-type Ca2+-channels on an optogenetically paced muscular pump in Caenorhabditis elegans. Scientific Reports 5:14427 | DOI: 10.1038/srep14427.
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Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee J-S, Gottschalk A, Brose N, Schultz C, Trauner D. (2016) Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology 12: 755-62
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Safdie G, Liewald JF, Kagan S, Battat E, Gottschalk A, Treinin M. (2016) RIC-3 phosphorylation enables dual regulation of excitation and inhibition of C. elegans muscle. Mol. Biol. Cell 27:2994-3003.
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Steuer Costa W, Yu S-c, Liewald JF, Gottschalk A. (2017) Fast cAMP modulation of neurotransmission via neuropeptide signals and vesicle loading. Curr. Biol. 27: 495-507
