Manfred Jung
Pharmaceutical and medical chemistry
Freiburg Institute for Advanced Studies
Germany
Biography
Manfred Jung studied pharmacy in Marburg and was promoted there in 1993 to Prof. W. Hanefeld in Pharmaceutical Chemistry. From 1993-94 he worked with a DFG scholarship as postdoctoral student in the group of Prof. T. Durst (Department of Chemistry, University of Ottawa). From 1994 onwards, he worked as a working group leader at the Institute for Pharmaceutical Chemistry at the University of Münster. During this time he was awarded a two-year postdoctoral fellowship from the German Pharmaceutical Society (DPhG). In 2000 he qualified as a pharmacist for pharmaceutical chemistry (mentor Prof. B. Unterhalt) and received the joint junior prize for medical chemistry of the DPhG and the GDCh. In 2003 he was appointed to a C3 Professorship for Pharmaceutical Chemistry at the University of Freiburg. In 2010, he received a reputation as a W3 Professorship for Pharmaceutical Chemistry at the University of Mainz. He rejected this reputation and accepted a course offered by the University of Freiburg to a W3 professorship for pharmaceutical chemistry. The working group is concerned with the synthesis of new inhibitors and the development of screening methods for the identification of new epigenetic drugs. He is a member of national research groups (SPP1463) and international (EU SEtTReND) research groups in the area of ​​epigenetics and co-speaker (spokesman R. Schüle) of the SFB initiative "Medical Epigenetics - MEDEP".
Research Interest
His research focus is on chemical epigenetics.
Publications
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Induction of human globin gene expression by histone deacetylase inhibitors. H. Cao, G. Stamatoyannopoulos, M. Jung; Blood 103 (2004), 701-709.
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Identification of selective inhibitors of NAD + -dependent deacetylases using phenotypic screening in yeast. M. Hirao, J. Posakony, M. Nelson, H. Hruby, M. Jung, JA Simon, A. Bedalov; J. Biol. Chem . 278 (2003) 52773-52783.
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A Non-Isotopic Assay for Histone Deacetylase Activity. K. Hoffmann, G. Brosch, P. Loidl, M. Jung; Nucleic Acids Res . "27 (1999) 2057-2058.