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Milena Bertolotti


Immunobiology
Freiburg Institute for Advanced Studies
Germany

Biography

Milena Bertolotti is currently working as a post-doctoral researcher in the group of Prof. Michael Reth, where I study the nanoscale organization of the B cell receptor (BCR) redox machinery. After obtaining my Bachelor's degree in Biotechnology at the University of Milano-Bicocca in Italy, I started my PhD at the International PhD School of "Molecular Medicine" at the University of Vita-Salute San Raffaele. I was able to determine the effect of the AQP8-mediated hydrogen peroxide transport on the subject. In 2008 and 2009, Prof. Sue Goo Rhee at the Ewha Womans University, in Seoul, Germany, where I analyzed the antibody production in various redox-related genes knock-out mice. From 2010 to 2015 I have also worked as a teaching assistant at the University of Vita-Salute San Raffaele, lectures in "Cell and molecular biology" for the degree course in "Medicine and Surgery". I was a Master Thesis supervisor for some students of the MSc in "Industrial Biotechnology" and MSc in "Biology" at the University of Milano-Bicocca. I am a member of the Society for Free Radical Biology and Medicine and of the Differentiation Cell Biology Association, which is my research expertise focused on the fields of cell biology, immunology and redox signaling.

Research Interest

Her research interest are focused on the fields of cell biology, immunology and redox signaling.

Publications

  • Bertolotti M., Sitia R, Rubartelli A, On the redox control of B lymphocyte differentiation and function antioxidant redox signal . 2012 May, 16 (10): 1139-49

  • Bertolotti M., Bestetti S, García-Manteiga JM, Medraño-Fernandez I, Dal Mas A, Malosio ML, Sitia R., Tyrosine kinase signal modulation: a matter of H 2 O 2 membrane permeability? Antioxidant redox signal . 2013 Nov, 19 (13): 1447-51.

  • Bertolotti M, Farinelli G, Galli M, Aiuti A, Sitia R., AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells. J Leukoc Biol . 2016

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