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Ralf Baumeister


Bioinformatics and Molecular Genetics
Freiburg Institute for Advanced Studies
Germany

Biography

Ralf Baumeister is a professor of Bioinformatics and Molecular Genetics (Biology) and of Molecular Medicine & Cell Biology (Medicine) at the University of Freiburg and is a member of the newly established Freiburg Center for Systems Biology (ZBSA). The results of this study are summarized in the following table: Caenorhabditis elegans for target identification, validation, and drug screenings. In order to exploit the superb genetics and neurobiology of C. elegans for drug discovery, he cofounded in 1999 EleGene AG, (Martinsried, Germany). Master's degree in Microbiology, Human Genetics, Biochemistry, and Computer Science, 1987, and his PhD from Erlangen University, 1992. Work for this doctoral thesis included research visits at the Karolinska Institute, Stockholm, and at the Institute of Crystallography, Berlin. During his postdoc research until 1995 at Harvard Medical School / Mass. General Hospital, Boston, USA, studied nervous system development in C. elegans in the lab of Gary Ruvkun. Starting in 1996, Baumeister became a group leader in neurogenetics at the Genzentrum and in 2000 Professor of Biochemistry at the University of Munich. He accepted a position at the University of Freiburg in September 2003 as a recipient of the "Qualityoffensive" Program donated by the State of Baden-Württemberg. In October 2006, Baumeister declined to offer the Chair for Systems Biology at Imperial College, London and as Director of CISBIC (Center of Integrative Systems Biology at Imperial College) to continue his work as Director of the Center of Systems Biology at Freiburg. He is affiliated today with the Faculty of Biology and the Faculty of Medicine at the University of Freiburg. Since 2007 he is Director of the Institute of Biology 3 and of the section LIFENET of FRIAS - Freiburg Institute for Advanced Studies

Research Interest

His research interest focuses on Insulin signalling, stress response and aging, genes associated with neurodegenerative diseases and protein turnover (Alzheimer's, Parkinson's, muscular dystrophies), transcriptional regulation.

Publications

  • L. Rizzini, J. Favory, C. Cloix, D. Faggionato, A. O'Hara, E. Kaiserli, R. Baumeister, E. Schafer, F. Nagy, G. Jenkins, R. Ulm: Perception of UV-B by the Arabidopsis UVR8 Protein Science , 2011; 332 (6025): 103-106

  • S. Liu, E. Schulze, R. Baumeister: Temperature- and Touch-Sensitive Neurons. Plos One , 2012; 7 (3): e32360.

  • C. Fatouros, GJ Pir, J. Biernat, SP Koushika, E. Mandelkow, EM Mandelkow, E. Schmidt, R. Baumeister: Inhibition of Tau Aggregation in a Novel C. elegans Model of Tauopathy mitigates proteotoxicity. Hum Mol Genet , 2012.

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