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Wolfgang R. Hess


Genetics and Experimental Bioinformatics
Freiburg Institute for Advanced Studies
Germany

Biography

Wolfgang R. Hess studied biology at the University of Rostock and the Humboldt-University Berlin, Germany, where he obtained his doctorate in 1990 and the habilitation in 1999. After a post-doc at the CNRS institute in Roscoff, France, running a junior research group at the Humboldt-University Berlin and pursuing research projects as a visiting scientist at the Friedrich-Miescher Institute in Basel, Switzerland and at the Massachusetts Institute of Technology, US, in 2003 funding director of the Ocean Genome Legacy Foundation, a spin -off from the biotech company New England Biolabs. In 2004 he became appointed as a Professor for Experimental Bioinformatics and in 2008 as a Full Professor for Genetics at the University of Freiburg, Germany. He has been a William Evans guest professor at the University of Otago, New Zealand.

Research Interest

His current research focuses on MapRNA: Mapping RNA-RNA pairings in vivo in bacteria and their importance in almost acclimation processes

Publications

  • The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by targeting glutamine synthase inactivation factor IF7. Proc. Natl. Acad. Sci. USA 112 , E6243-52.

  • Reimann V., Alkhnbashi O., Saunders SJ, Scholz I., Hein S., Oven R., Hess WR (2017) Structural constraints and enzymatic promiscuity in the Cas6-dependent generation of crRNAs. Nucleic Acids Research 45 , 915-925.

  • Georg J., Kostova G., Vuorijoki L., Schön V., Kadowaki T., Huokko T., Baumgartner D., Müller M., Klähn S., Allahverdiyeva Y., Hihara Y., Futschik M., Aro EM , Hess WR (2017) Acclimation of oxygenic photosynthesis to iron starvation is controlled by the sRNA IsaR1. Current Biology 10 , 1425-1436 .

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