Dr. Anja Schneider
Professor
Center for Neurodegenerative Diseases
German Centre for Neurodegenerative Diseases (Deutsches Zentrum für Neurodegenerative Erkrankungen)
Germany
Biography
Anja Schneider studied medicine in Heidelberg and Hamburg and graduated in 2001. After a postgraduate study in molecular biology at Hamburg university and a doctoral thesis project on tau phosphorylation in the labs of Prof. E. Mandelkow (Max-Planck group for structural molecular biology, Hamburg, Germany) and Prof. B.T. Hyman (Harvard Medical School, Boston, USA) she received her MD in 2003. Between 2004 and 2007 she worked as a postoc on amyloid aggregation in the lab of Prof. M. Simons at MPI for experimental medicine. In 2010 she received the venia legend (“Habilitation”) at Göttingen University. Since 2010 she is a principal investigator at the German Research Foundation funded research center “molecular physiology of the brain” and cluster of excellence “microscopy in the nanometer range” CMNBP in Göttingen. In 2012 she received a Heisenberg fellowship from the German Research Foundation followed by a W2 professorship for translational dementia research at the university medical center and the DZNE Göttingen. Between 2012 and 2016 her lab was hosted by the MPI for Experimental Medicine in Göttingen . After a residency at the department for neurology, university Tübingen und at the department for psychiatry, university Göttingen, she received her board certification in psychiatry and psychotherapy in 2010 and a certificate in gerontopsychiatry and gerontopsychotherapy in 2013. Between 2009 and 2016 she was head of the memory clinic and between 2011 and 2016 senior consultant at the department of psychiatry of the university medical center Göttingen. From 2011 to 2016 Anja Schneider was deputy head of the clinical dementia center at the university medical center in Göttingen. Between 2011 and 2013 she acted as coordinator of clinical research at the DZNE Göttingen. In 2016 she received a W3 professorship for clinical dementia research at DZNE and university Bonn.
Research Interest
The translational dementia research group at DZNE Bonn investigates the cell biological mechanisms of neurodegenerative diseases with a focus on transneuronal spreading and clearance of pathological . Another focus of our research is the function of extracellular vesicles/exosomes in the central nervous system and the development of novel diagnostic and prognostic biomarkers in neurodegenerative diseases. An important aspect of our work is the translation from basic research to clinical application and vice versa, to explore questions based on clinical research findings within animal and cell models.
Publications
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In vivo markers of Parkinson's disease and dementia with Lewy bodies: current value of the 5G4 α-synuclein antibody. Maetzler W, Pilotto A, Apel A, Deuschle C, Kuebart G, Heinzel S, Liepelt-Scarfone I, Schulte C, Reusch D, Schleicher E, Rothfuss O, Schneider A, Dodel R, Gasser T, Berg D. Acta Neuropathol. 2014 Dec;128(6):893-5.
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Neuron-to-neuron α-synuclein propagation is dependent on neuronal integrity. Ulusoy A, Musgrove RE, Rusconi R, Klinkenberg M, Helwig M, Schneider A, Di Monte DA. Acta Neuropathologica Comm.
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Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH, Schneider A. Acta Neuropathol. 2015 Mar 17.