Dr. Manuela Neumann
Professor
Center for Neurodegenerative Diseases
German Centre for Neurodegenerative Diseases (Deutsches Zentrum für Neurodegenerative Erkrankungen)
Germany
Biography
Manuela Neumann studied medicine at the University of Munich (LMU) and University of Goettingen. For her doctoral thesis, she performed studies on the prion protein gene and its role in familial and transmissible prion diseases (supervisor Prof. Dr. Kretzschmar). She received her training as a specialist in neuropathology at the Institute of Neuropathology, University Göttingen and Munich. During this time she was also the scientific coordinator for the German brain bank network "Brain-Net". From 2005-2006 she was a visiting scientist at the laboratory of Drs John Trojanowski and Virginia Lee at the Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, USA. After her return to the Institute of Neuropathology she worked as independent group leader and habilitated in the same year at the LMU on the molecular neuropathology of α-synucleinopathies and tauopathies. In 2008 she was appointed Assistant Professor of Experimental Neuropathology at the University of Zurich. In June 2012 she accepted an appointment as chair of neuropathology at the University of Tübingen and the Center for Neurodegenerative Disease Research.
Research Interest
Prof. Neumann’s main research area is the molecular pathology of neurodegenerative diseases with focus on frontotemporal dementia and amyotrophic lateral sclerosis. She was honored for her work with several awards, including the prestigious research award from the Hans & Ilse Breuer Foundation in 2012.
Publications
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FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations. Neumann M, Bentmann E, Dormann D, Jawaid A, DeJesus-Hernandez M, Ansorge O, Roeber S, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ang L-C, Bilbao J, Rademakers R, Haass C, and Mackenzie IRA (2011). Brain 134:2595-2609.
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Neuropathological background of phenotypical variability in frontotemporal dementia. Josephs KA, Hodges JR, Snowden JS, Mackenzie IR, Neumann M, Mann DM, and Dickson DW (2011). Acta Neuropathol 122:137-153.
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Advances in understanding the molecular basis of frontotemporal dementia. Rademakers R, Neumann M, and Mackenzie IR (2012). Nat Rev Neurol 8:423-434.