Franz Bracher
Medicinal Chemistry
Institut Pasteur de Bangui
Germany
Biography
Prof. Dr. Franz Bracher Department Pharmazie - Zentrum für Pharmaforschung - Ludwig-Maximilians-Universität München Butenandtstr. 7, Haus C 81377 München,Studied pharmacy at the LMU Munich 1986 PhD in Pharmaceutical Chemistry, LMU Munich 1986-1987 Postdoctoral Researcher at the Department of Organic Chemistry, University of Geneve/Switzerland 1991 Habilitation, University of Marburg 1992-1997 C3 Professor, University of Braunschweig Since 1997 C4 Professor for Pharmaceutical Chemistry, LMU Munich
Research Interest
Natural product chemistry (synthesis, biological activities) Inhibitors of ergosterol and cholesterol biosynthesis as new drugs Development of new, selective kinase inhibitors
Publications
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K. Huber K, L. Brault, O. Fedorov, C. Gasser, P. Filippakopoulos, A. N. Bullock, D. Fabbro, J. Trappe, J. Schwaller, S. Knapp, F. Bracher: 7,8-Dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes, J. Med. Chem. 55, 403-413 (2012)
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M. König. C. Müller, F. Bracher: Stereoselective synthesis of a new class of potent and selective inhibitors of human Δ8,7-sterol isomerase Bioorg. Med. Chem. 21, 1925-1943 (2013)
