Stewart A Anderson
Neurology
Institut Pasteur de Bangui
Germany
Biography
Professor of Psychiatry, I am a Children's Hospital of Philadelphia-based faculty in the Department of Psychiatry at UPenn. The focus of my laboratory concerns the molecular and cellular mechanisms that govern the development of the mammalian forebrain. We use mouse genetics, forebrain slice and dissociated culture techniques, as well as mouse and human pluripotent stem cells in cell culture and transplantation experiments to study the fate determination of interneurons of the cerebral cortex. We are particularly interested in understanding the molecular underpinnings behind the fate determination of subclasses of GABAergic interneurons implicated in the neuropathology of autism and schizophrenia.
Research Interest
Cell and Molecular Biology Neuroscience
Publications
-
Cheslow Lara, Alvarez Jorge Iván Glial-endothelial crosstalk regulates blood-brain barrier function. Current opinion in pharmacology 26: 39-46, 2016.
-
Mayo Lior, Cunha Andre Pires Da, Madi Asaf, Beynon Vanessa, Yang Zhiping, Alvarez Jorge I, Prat Alexandre, Sobel Raymond A, Kobzik Lester, Lassmann Hans, Quintana Francisco J, Weiner Howard L IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain : a journal of neurology 139: 1939-57, 2016.