Stefan Kins
Department of Biology
Kaiserslautern University of Technology
Germany
Biography
Prof. Stefan Kins received his PhD at Max Planck Institute for Brain Research, Frankfurt, during the period of 1996. Currently, he is working as Professor for Human Biology and Human Genetics, Dept. Biology, University Kaiserslautern, Germany. His research has included, Alzheimer Disease, APP function and transport
Research Interest
APP function and transport
Publications
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Kuan Y-H, Grübl T, Soba P, Eggert S, Nesic I, Kirsch J, Beyreuther K, Kins S. The processing and anterograde transport of APP, APLP1 and APLP2 is affected by the carboxyl-terminal binding partner PAT1a. J Biol Chem. 2006;281(52):40114-23
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Rusu P, Jansen A, Soba P, Kirsch J, Löwer A, Merdes G, Kuan Y-H, Jung A, Beyreuther K, Kjaerulff O, Kins S. Axonopathy in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity, Eur. J. Neurosci., 2007;25(4):1079-86
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Back S, Haas P, Tschäpe J-A, Gruebl T, Kirsch J, Müller U, Beyreuther K, Kins S. In neurons APP can be transported independent of any sorting signal to the axonal and dendritic compartment. J Neurosci Res. 2007;25:1079-86
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Deboer SR, You Y, Szodorai A, Kaminska A, Pigino G, Nwabuisi E, Wang B, Estrada-Hernandez T, Kins S, Brady ST, Morfini G. Conventional Kinesin holoenzymes are composed of heavy and light chain homodimers. Biochemistry. 2008;47:4535-43