Dr. Erik Keimpema
Network of European Neuroscience Institutes
Network of European Neuroscience Institutes (ENI-NET)
Germany
Biography
Dr. Erik Keimpema Medical University of Vienna – The European Neuroscience Institute - Medical University of Vienna
Research Interest
My research interests encompass describing the molecular machinery underlying the signals important for the proper development of the fetal brain. These include endocannabinoids, which are lipid signals promoting neurite outgrowth and growth cone motility, both in cortical pyramidal cells and basal forebrain cholinergic neurons (Keimpema, 2010-J Neurosci; Keimpema, 2013-PNAS). We also showed that endocannabinoid signaling can mediate chemorepulsion by regulating Robo/Slit signaling in cortical pathfinding (Alpar, 2014-Nat Commun). Our studies on the molecular organization of endocannabinoid signaling eventually led to the description of a model of cannabis sensitivity in the developing fetal brain (Keimpema et al., 2011-TiPS).
