Dr Johannes Gräff
European neuroscience institute
Network of European Neuroscience Institutes (ENI-NET)
Germany
Biography
Dr Johannes Gräff The Brain Mind Institute at EPFL, Laboratory of Neuroepigenetics – The Brain Mind Institute Lausanne
Research Interest
To answer these questions, our lab focuses on the emerging field of neuroepigenetics. "Epi-genetic" mechanisms, i.e. modifications to the chromatin that regulate gene expression without changing the DNA sequence itself, have not only been shown to react to fluctuating environmental contingencies, but also to encode the cell fate of neurons and other cell types during development. With this Janus-faced property of being at once dynamic and stable, we believe that epigenetic mechanisms harbor the potential to better explain the molecular processes that govern learning, memory and memory loss. In extension, because epigenetic mechanisms are also amenable to pharmacological intervention, they might constitute a novel angle on how to counteract memory loss and resilient traumatic memories.
