Josef Kittler

Biography

Professor Josef Kittler Department of Neuroscience, Physiology and Pharmacology – The European Neuroscience Institute at University College London

Research Interest

Nerve cells in the brain have a highly spatially diverse cellular and subcellular architecture including axon, cell body, and dendrites as major cellular compartments, in addition to subcellular membrane microdomains such as spines, synapses and the secretory and endosomal networks. To ensure efficient signaling between neurons, and to ensure that the correct levels of neuronal network activity are maintained, it is critical that mechanisms exist to tightly regulate the selective transport and localisation of ion channels, receptors and organelles to specific neuronal locations. We are interested in understanding the contribution played by intracellular transport and membrane trafficking of channels, transporters and organelles in regulating the formation, activity and plasticity of synapses.