Gerhard Erkel
Professor
Department of Microbiology
State Research Center for Optics and Material Sciences
Germany
Biography
1990: Dr. rer. nat (Ph. D.) University of Kaiserslautern 1990-1991: Research Associate Group of Biotechnology, University of Kaiserslautern (Prof. Dr. T. Anke). 1991-1992: Postdoc at New York University, Dept. of Microbiology in the group of Prof. W. Maas, New York. 1992-1998: Research Associate, Group of Biotechnology, University of Kaiserslautern (Prof. Dr. T. Anke). 1999: Habilitation (Biotechnologie), University of Kaiserslautern. 1998-2003: Research Associate, Institute of Biotechnology and Drug Research. Since Oct. 2003: Research Associate, Group of Biotechnology, University of Kaiserslautern (Prof. Dr. T. Anke).
Research Interest
The main aims of our research are (1) the identification and isolation of bioactive compounds from fungi, which interfere with the inducible transcription of disease-related genes with particular reference to inflammation, allergy and cancer; (2) the development of test systems; and (3) mode-of-action studies of new compounds inhibiting signal transduction pathways in mammalian cells.
Publications
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Rether J, Erkel G, Anke T, Bajtner J, Sterner, O (2008) Imidazo[1,2-?]pyridine derivatives as inhibitors of TNF-? expression in T cells. Bioorg. Med. Chem 16: 1239-1241.
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Erkel G, Wisser G, Anke T(2007)Influence of the fungal NF-?B inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells. Int. Immunopharmacol 7: 612-624.
