Martin J. Lohse
Professor Chair of Pharmacology
Professor Chair of Pharmacology;
The Julius Maximilian University of Wurzburg
Germany
Biography
Education and Training 1974 - 1981 Studies in medicine and philosophy, Universities of Göttingen (Germany), London (UK) and Paris (France) 1978 - 1981 MD thesis, Max Planck Institute of Biophysical Chemistry, Department of Neurobiology and University of Göttingen (Germany) 1988 Habilitation, Pharmacology and Toxicology, University of Heidelberg (Germany) Positions and Employment 1983 - 1988 Post-Doctoral Fellow, Institute of Pharmacology, University of Heidelberg (Germany) – U. Schwabe 1988 - 1990 Research Assistant/Assistant Prof., Howard Hughes Medical Institute, Duke University, Durham (NC, USA) – R.J. Lefkowitz 1990 - 1993 Group leader, Gene Center, University of Munich/MPI Biochemistry, Martinsried (Germany) Since 1993 - Professor and Chair, Institute of Pharmacology and Toxicology, University of Würzburg (Germany) Since 2001 - Chairman, Rudolf Virchow Center /DFG-Research Center for Experimental Biomedicine, University of Würzburg (Germany) Since 2003 - Director Graduate Schools University of Würzburg Since 2009 - Vice President for Research, University of Würzburg
Research Interest
Main interests Molecular pharmacology, receptors and signal transduction, cardiovascular pharmacology  Ongoing research Mechanismen der Aktivierung und Inaktivierung von Rezeptoren
Publications
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Ligand-Specific Restriction of Extracellular Conformational Dynamics Constrains Signaling of the M2 Muscarinic Receptor. Experimental and mathematical analysis of cAMP nanodomains. cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons. β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle.
