Dr. Alessandro Torgovnick Donadello
DNA Damage and Cancer Lab
University of Cologne
Alessandro Torgovnick’s scientific career started in the Lab of Gene Expression of Prof. Massimo Levrero, at CRS Regina Elena Cancer Center of Rome where he obtained his master degree with a thesis entitled "Modulation of NF-kB's transcriptional activity by acetylases and deacetylases”. Afterward, he moved to the C. elegans Unit directed by Dr. Natascia Ventura, in the Lab of Prof. Roberto Testi at the University of Rome "Tor Vergata", where he succesfully applied for a PhD program in Immunology and Applied Biotechnologies. During his PhD training, he investigated the role of mitochondrial dysfunction in aging and neurodegenerative diseases, using the nematode C. elegans as a model organism, and he won a short-term EMBO fellowship which allows him to visit the Lab of DNA Damage and Ageing of Prof. Björn Schumacher (CECAD, University of Cologne, Germany). He is actually working, as a post-doc, in the Lab of Prof. Christian Reinhardt (University Hospital of Cologne, Cologne, Germany) where he is using genetically engineered mouse models to study p53-dependent tumor suppressive pathways.
Molecular Biology, Cancer Therapy, Ageing, DNA Repair Mechanisms, DNA Damage Response, Cell cycle Checkpoints, Epigenetics