Dr. Wolf-michael Weber
Professor
Biology
University of Munster
Germany
Biography
1976-1986 student in the study program "Biology and biochemistry", University of Saarland, Saarbrücken, Germany Diploma, Thesis: "Influence of IR laser light on metabolic rates of cell cultures of Saccheromyces cervisiae " - March 1987 - June 1989 PhD student at the Max Planck Institute for Biophysics, Frankfurt / Main, Germany (Prof. Dr. W. Schwarz) PhD, Thesis: "Comparison of endogenous glucose uptake systems of Xenopus oocytes with foreignated glucose transporters" - July 1989 - December 1990 Head Research & Development at Heka Electronics, Lambrecht, Germany - January 1991 - May 1992 Post-doc at the Institute of Veterinary Physiology, Free University of Berlin, Germany (Prof. Dr. W. Clauss) - June 1992 - March 1993 Post-doc at the Institute of Animal Physiology, Justus-Liebig -University, Giessen, Germany - April 1993 - March 1999 Assistant professor (C1), Head Cell Biology and Electrophysiology, Institute of Animal Physiology, Justus Liebig University, Giessen, Germany - December 1996 Habilitation in "Animal Physiology", Thesis: *** "" Comparison of endogenous and labeled transport systems in oocytes of Xenopus laevis ", Venia legendi - April 1999 -August 2002 Assistant Professor, Head Electrophysiology, KU Leuven, Belgium, Faculty of Medicine, Department of Molecular Biology, Laboratory of Physiology - Since April 2002 Full Professor, Head of the Transport Group Muenster
Research Interest
Epithelial Na Channel (ENaC); CFTR and cystic fibrosis; Ca-inactivated Cl-channel (CaIC); Endogenous ion channels in Xenopus laevis oocytes.
Publications
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Bangel-Ruland Nadine, Sobczak Katja, Christina Tina, Kentrup Dominik, Langhorst Hanna, Kusche-Vihrog Kristina, Weber Wolf-Michael. 2010, Characterization of the epithelial sodium channel delta-subunit in human nasal epithelium. American Journal of Respiratory Cell and Molecular Biology , No. 42: 498-505.
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Clark KL, Hughes SA, Bulsara P, Coates J, Moores K & a. 2013, Pharmacological Characterization of a Novel ENaCalpha siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis. Molecular Therapy Nucleic Acids 2, No. 65.
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Leier G, Bangel-Ruland N, Sobczak K, Knieper Y, Weber WM . 2012, Sildenafil acts as a potentiator and corrector of CFTR but may be appropriate for the treatment of CF lung disease. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology 29, no. 5-6: 775-90.
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Bangel-Ruland N, Tomczak K, Fernández EF, Leier G, Leciejewski B & a. 2013, CFTR-mRNA delivery: a novel alternative for cystic fibrosis gene therapy. The journal of gene medicine 2013.
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Hardin, Bertoni, Kleinsmith . 2016, Beckers World of Cell Specialized editor of the German edition . 8. Ed . : Pearson.
