Patrick Kobina Arthur
Department of Biochemistry, Cell and Molecular Biology
University of Ghana
Patrick Kobina Arthur is currently working as a Lecturer in Department of Biochemistry, Cell and Molecular Biology, University of Ghana.
Isolation and characterization of novel bioactive compounds from organisms originating from tropical-equatorial biodiversity hotspots, namely: Basidiomycetes (Wood Decaying Fungi), Ascomycetes (Marine Endophytic Fungi) Microalgae Actinomycetes Targeted Proteomics (Selected Reaction Monitoring) of Mycobacteria (in collaboration with the Aebersold Lab, ETH-Zurich, Switzerland). Chemical proteomics of target proteins in human parasites to specific novel bioactives and vice versa as well as corresponding off-target cellular proteins in humans Comparative and functional proteomics on target proteins & specific novel bioactives Clinical proteomics of novel bioactives, identification of biomarkers for in vivo activities Protein Biochemistry - Establish a library of 100 enzymes for molecular biology applications Molecular and structural dynamics of ribonucleoprotein complexes.
Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma. Koebernick K, Loeber J, Arthur PK, Tarbashevich K, Pieler T. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16148-53.
Expression, purification and analysis of the activity of enzymes from the pentose phosphate pathway. Arthur PK, Alvarado LJ, Dayie TK., Protein Expr Purif. 2010 Nov 23.
Schubert, O. T., Mouritsen, J., Ludwig, C., Rost, H. L., Rosenberger, G., Arthur, P. K., Claassen, M., Campbell, D. S., Sun, Z., Farrah, T., Gengenbacher, M., Kaufmann, S.H.E., Moritz, R. L., Aebersold, R. (2013) 'The Mtb Proteome Library: A Resource of Assays to Quantify the Complete Proteome of Mycobacterium tuberculosis', Cell Host Microbe 13(5): 602-12