Stephen Holgate
Immunopharmacology and Honorary Consultant Physician
Biological Co
Greece
Biography
Professor Stephen Holgate is Medical Research Council Clinical Professor of Immunopharmacology and Honorary Consultant Physician within Medicine at the University of Southampton. Stephen Holgate is Medical Research Council Clinical Professor of Immunopharmacology at the Faculty of Medicine, Southampton, UK. After completing his medical training in London he spent 2 years at Harvard Medical School to acquire skills in allergic disease mechanisms. On returning to Southampton in 1980, he set up a research group focused on the mechanisms of asthma. He has utilized many approaches to study this disease including epidemiology, genetics, pathology, microbiology and immunology, pharmacology and experimental medicine.BSc Biochemistry (Class I), London University (1968) MB BS, Medicine/Surgery, London University (Charing Cross Hospital Medical School) (1971) MD, Asthma Research, London University (1979) DSc, Inflammatory Basis of Asthma, University of Southampton (1991)MRCP (UK), Royal College of Physicians (1973) FRCP, Royal College of Physicians of London (1984
Research Interest
The Pathophysiology of asthma across the lifecourse The role of the epithelium in asthma. My research has focused on the causes of human asthma and its treatment. After establishing the key role that mast cells and other key effector cells play in triggering the acute allergic inflammatory response in asthma, I have focused my attention upon the mechanisms of disease chronicity and variability across the lifecourse.