Evagelia G. Kranias
Investigator
Cardiology
BRFAA
Greece
Biography
She holds Doctorate degree from Northwestern University in the year 1974. She is Affiliated Investigator in Biomedical Research Foundation of the Academy of Athens
Research Interest
Her research interest lie in unraveling the mechanisms underlying the impaired regulation of sarcoplasmic reticulum (SR) Ca-cycling in heart failure with the aim to provide fundamental mechanistic insights and to identify new therapeutic modalities.
Publications
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Fan, G.C., Zhou, X., Wang, X., Song, G., Qian, J., Nicolaou, P., Chen, G., Ren, X., Kranias, E.G. Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity. Circ Res. 103(11):1270-9, 2008. PMCID:2763388
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Fan, G.C., Yuan, Q., Song, G., Wang, Y., Chen, G., Qian, J., Zhou, X., Lee, Y.J., Ashraf, M., Kranias, E.G. Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1. Circ Res. 99(11):1233-42, 2006. PMID:17068291
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Haghighi, K., Kolokathis, F., Gramolini, A.O., Waggoner, J.R., Pater, L., Lynch, R.A., Fan, G.C., Tsiapras, D., Parekh, R.R., Dorn, G.W. 2nd, MacLennan, D.H., Kremastinos, D.T., Kranias, E.G. A mutation in the human phospholamban gene, deleting arginine14, results in lethal, hereditary cardiomyopathy. Proc Natl Acad Sci U S A. 103(5):1388-93, 2006. PMCID:1360586
