Charalamp
IMBB Group Leader
Development & Gene Expression
FORTH Institute of Molecular Biology & Biotechnology
Greece
Biography
Charalampos G. Spilianakis IMBB Group Leader (Assistant Professor, Univ. of Crete)
Research Interest
The main objective of our laboratory is to apply a combination of biocomputing, molecular, biochemical, imaging and genetic approaches in order to identify and characterize protein complexes that generate and/or maintain long range chromosomal interactions in cell populations of the innate and adaptive immune system. We aim to provide substantial information on how the genome is shaped as a whole and how the nuclear structure patterns in the context of distinct subnuclear microenvironments regulate global gene expression (3D epigenetics).