Doris W T Au
Professor
Chemistry
City University of Hong Kong
Hong Kong
Biography
The DA lab is interested in toxicology research. Her team applies omics, molecular, biochemical and cellular approaches, together with relevant whole organismal phenotypic endpoints, to identify underlying mechanisms and to predict population level consequences. Her current research is focused on the investigation of multigenerational toxicity, with special interest in studying transgenerational inheritance of skeletal deformity, reproductive and immune impairments induced by environmental contaminants and physical stresses (including endocrine disruptors, polycyclic aromatic hydrocarbons, hypoxia) using various medaka models. The primary goals are for elucidating the underlying epigenetic/genetic mechanisms, developing novel prognostic/diagnostic epigenetic biomarkers and assessment of ecological and public health risks. She also has a keen interest in studying telomere and telomerase biology in fish and developing medaka as an alternative vertebrate model for aging research. Dr Au has over 120 peer reviewed publications and delivered over thirty invited symposia/plenary/ keynote lectures.
Research Interest
Environment and human health
Publications
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Wang SY, et al, Au DWT, Wong AST, Kong RYC, and Wu RSS (2016) Hypoxia causes transgenerational impairments in reproduction of fish. Nature Communication Vol 7, p 12114, doi: 10.1038/ncomms12114.
