Xu Gang
Principle Lecturer
Pharmacological Studies and Translational Studies
Consun Chinese Medicines Research Centre for Renal Diseases
Hong Kong
Biography
Academic qualifications: 1981-1987 B. Med. Faculty of Medicine, China Medical University, China, 1989-1992 M.S. Department of Surgery, China Medical University, China 1994-1998 M.D. & Ph.D. Department of Surgery, Shimane Medical University, Japan, Professional Experience: 1987-1989 Intern/Resident Department of Surgery, People’s Hospital of Liaoning Province, China 1989-1993 Resident/Chief Resident Department of Surgery, China Medical University, China 01/1993-03/1994 Clinical Research Fellow Department of Surgery, Shimane Medical University, Japan 04/1998-05/2003 Post-doctoral Fellow Islet Transplantation and Cell Biology, Joslin Diabetes Centre, Harvard Medical School, USA 05/2003-03/2006 Senior Scientist Lifescan, Johnson & Johnson, USA 03/2006-05/2007 Assistant Research Centre for Regenerative Biology, University of Connecticut, USA Professor Since 05/2007 Assistant Professor Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong 03/2010-05/2013 Associate Director Hong Kong Institute of Diabetes and Obesity, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Present academic position: 06/2013- Principle Lecture Biomedical Science Program, School of Chinese Medicine, Hong Kong Baptist University
Research Interest
Pathogenesis of type 2 diabetes and drug discovery.
Publications
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The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells. Cell Transplant.
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*. Pharmacological reduction of free fatty acids restores the efficacy of incretin-based therapies in diabetic mouse models through beta-cell GLP-1 receptor signaling.
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Unfolded Protein Response Is Required for the Definitive Endodermal Specification of Mouse Embryonic Stem Cells via Smad2 and beta-catenin Signaling
