Pathology Experts

Chan, Kwan Chee Allen

Chemical Pathology
Li Ka Shing Institute of Health Sciences
Hong Kong


Professor Allen Chan is currently appointed as Professor at the Department of Chemical Pathology at the Chinese University of Hong Kong. He graduated from the University of Hong Kong in 1996 and obtained his PhD in molecular biology under the supervision of Professor Dennis Lo. He is a fellow of the Royal College of Pathologists of Australasia, Hong Kong College of Pathologists and Hong Kong Academy of Medicine. He is also a member of the Royal College of Physician. Professor Chan’s main research interest is on the development of new diagnostic approaches based on circulating DNA analysis. He is an inventor of the noninvasive prenatal test for Down syndrome using plasma DNA analysis in pregnant women. He has over 40 patents/patent applications on molecular diagnostics. Professor Chan has led a prospective trial involving over 20,000 subjects to investigate the use of liquid biopsy for the screening of early nasopharyngeal carcinoma. Apart from research, Professor Chan is also enthusiastic to teaching. He has received a total of four Teacher of the Year Awards from the Faculty of Medicine, CUHK.

Research Interest

- Noninvasive prenatal testing (NIPT) - Cancer detection and monitoring


  • Chan KCA, Woo JKS, King A, Zee BCY, Lam WKJ, Chan SL, Chu SWI, Mak C, Tse IOL, Leung SYM, Chan G, Hui EP, Ma BBY, Chiu RWK, Leung SF, van Hasselt AC, Chan ATC, Lo YMD. Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer. New England Journal Of Medicine. 2017; 377(6): 513-522. doi: 10.1056/nejmoa1701717.

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