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Mary M.y. Waye

Research Professor
Medicine
Nethersole School of Nursing
Hong Kong

Biography

Dr. Waye received the degree of Bachelor of Science (Hon) from the University of Western Ontario, Canada, majoring in Bacteriology and Immunology and then took graduate work and received Ph.D. in Medical Biophysics at the University of Toronto , Canada . During her graduate period, she received support as a research student of the National Cancer Institute. On completing her Ph.D. she received a King George V Fellowship and received her post-doctoral training at the Laboratory of Molecular Biology, Medical Research Council, in Cambridge, UK as a National Cancer Institute Research Fellow. She did research in the Division of Protein and Nucleic Acid and later also received training in the Division of Structural Studies in Cambridge. She returned to the University of Toronto as an assistant professor. She has been at the Chinese University of Hong Kong since 1992. She was appointed as the founding director of the Croucher laboratory for Human Genomics in 2004.

Research Interest

Study of association of genetic variants with human conditions, including psychiatric disorders. Human genetic study of developmental dyslexia. Studies on twins and language development. Molecular characterization of gene functions using multidisciplinary approaches.

Publications

  • Liang WC, Fu WM, Wong CW, Wang Y, Wang WM, Hu GX, Zhang L, Xiao LJ, Wan DC, Zhang JF, Waye MM. (2015) The LncRNA H19 promotes epithelial to mesenchymal transition by functioning as MiRNA sponges in colorectal cancer. Oncotarget. 2015 Sep 8;6(26):22513-25

  • Rao S, Lam MH, Yeung VS, Wing YK, Waye MM. (2016) Association of HOMER1 rs2290639 with suicide attempts in Hong Kong Chinese and the potentially functional role of this polymorphism. Springerplus. 2016 Jun 17;5(1):767. eCollection 2016.

  • Liang WC, Liang PP, Wong CW, Ng TB, Huang JJ, Zhang JF, Waye MM, Fu WM. (2016) CRISPR/Cas9 Technology Targeting Fas Gene Protects Mice from Concanavalin-A Induced Fulminant Hepatic Failure. J Cell Biochem. 2016 Sep 1. doi: 10.1002/jcb.25722. [Epub ahead of print]

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