Chan Leung Franky
Professor
School of Biomedical Sciences
The Chinese University of Hong Kong
Hong Kong
Biography
Dr. CHAN Leung Franky is affiliated to the Department of School of Biomedical Sciences, CUHK . Dr. CHAN Leung Franky is currently providing services as Professor. Dr. CHAN Leung Franky has authored and co-authored multiple peer-reviewed scientific papers and presented works at many national and International conferences. Dr. CHAN Leung Franky contributions have acclaimed recognition from honourable subject experts around the world. Dr. CHAN Leung Franky is actively associated with different societies and academies. Dr. CHAN Leung Franky academic career is decorated with several reputed awards and funding. Dr. CHAN Leung Franky research interests include Hormonal carcinogenesis and cancer biology of prostate gland,Nuclear receptors-mediated signaling pathways in prostate gland development and prostate cancer,Tumor microenvironment, epithelial-mesenchymal-transition and hypoxia in prostate cancer,Molecular targeted therapy and immunotherapy of prostate cancer,Cancer stem cells in prostate cancer.
Research Interest
Hormonal carcinogenesis and cancer biology of prostate gland,Nuclear receptors-mediated signaling pathways in prostate gland development and prostate cancer,Tumor microenvironment, epithelial-mesenchymal-transition and hypoxia in prostate cancer,Molecular targeted therapy and immunotherapy of prostate cancer,Cancer stem cells in prostate cancer.
Publications
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Wu, D., Yu, S., Jia, L., Zou, C., Xu, Z., Xiao, L., Wong, K.B., Ng, C.F., and Chan, F.L. (2015). Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of CDKN1A (p21WAF1/CIP1) and SIRT1 genes. The Journal of Pathology, 236(1), 103-115.
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Wu, D., Cheung, A., Wang, Y., Yu, S., and Chan, F.L. (2016). The emerging roles of orphan nuclear receptors in prostate cancer. Biochimica et Biophysica Acta Reviews on Cancer, 1866(1), 23-36.
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Cai, G., Wu, D., Wang, Z., Xu, Z., Wong, K.B., Ng, C.F., Chan, F.L., and Yu, S. (2016). Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial-mesenchymal transition and remodeling of actin cytoskeleton organization. Oncogene, (advance online publication 20 June 2016; doi: 10.1038/onc.2016.227).
