Cheng Sze Lok Alfred
Associate Professor
School of Biomedical Sciences
The Chinese University of Hong Kong
Hong Kong
Biography
Dr. CHENG Sze Lok Alfred is affiliated to School of Biomedical Sciences, CUHK . Dr. CHENG Sze Lok Alfred is currently providing services as Associate Professor. Dr. CHENG Sze Lok Alfred has authored and co-authored multiple peer-reviewed scientific papers and presented works at many national and International conferences. Dr. CHENG Sze Lok Alfred contributions have acclaimed recognition from honourable subject experts around the world. Dr. CHENG Sze Lok Alfred is actively associated with different societies and academies. Dr. CHENG Sze Lok Alfred academic career is decorated with several reputed awards and funding. Dr. CHENG Sze Lok Alfred research interests include Transcriptional and epigenetic gene regulation in carcinogenesis,Molecular mechanisms underlying male predominance of liver cancer,Epigenetics of host-pathogen interactions,Nuclear hormone receptor regulation of cancer epigenome.
Research Interest
Transcriptional and epigenetic gene regulation in carcinogenesis,Molecular mechanisms underlying male predominance of liver cancer,Epigenetics of host-pathogen interactions,Nuclear hormone receptor regulation of cancer epigenome.
Publications
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Tsang, D.P., Wu, W.K., Kang, W., Lee Y.Y., Wu, F., Yu, Z., Xiong, L., Chan, A.W., Tong, J.H., Yang, W., Li, M.S., Lau, S.S., Li, X., Lee S.D., Yang, Y., Lai, P.B., Yu, D.Y., Xu, G., Lo, K.W., Chan, M.T., Wang, H., Lee, T.L., Yu, J., Wong, N, Yip, K.Y., To, K.F., Cheng A.S.L.* (2016). Yin Yang 1-mediated epigenetic silencing of tumor-suppressive microRANs activates nuclear factor-kB in hepatocellular carcinoma.  Journal of Pathology, 238(5), 651-664.
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Bai, A.H., Wu, W.K., Xu, L., Wong S.H., Go, M.Y., Chan, A.W., Harbord, M., Zhang, S., Chen, M., Wu, J.C., Chan, M.W., Chan, M.T., Chan, F.K., Sung, J.J., Yu, J., Cheng, A.S.L.*, Ng S.C.* (2016). Dysregulated lysine acetyltransferase 2B promotes inflammatory bowel disease pathogenesis through transcriptional repression of interleukin-10.  Journal of Crohn's and Colitis, 10(6), 726-734 (*Co-corresponding author).
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Wu, W.K.*, Yu, J., Chan, M.T., To, K.F., Cheng, A.S.L. (2016). Combinatorial epigenetic deregulation by Helicobacter pylori and Epstein-Barr virus infections in gastric tumorigenesis, Journal of Pathology, 239(3), 245-249.
