Prof Tse Wai Choi, Eric

Biography

 Tse graduated MBBS with the John Anderson Gold Medal from the University of Hong Kong. He also obtained a PhD at the University of Cambridge, and was awarded the Max Perutz Research Prize by the MRC Laboratory of Molecular Biology, Cambridge. Upon completion of clinical haematology training at Queen Mary Hospital, Dr. Tse has been appointed honorary consultant physician in the Department of Medicine. In addition to clinical research on the treatment of haematological malignancies, in particular T-cell and NK-cell lymphoid neoplasms, his basic and translational research have focused on the development of novel therapeutic approach in cancer treatment through identifying potential targets and understanding the fundamental biology of cancer. Dr. Tse has pioneered the development of intracellular antibodies in the therapy of cancer during his early stage of career.

Research Interest

He is currently examining the role of peptidyl-prolyl-isomerase PIN1 and its interplay with CKS proteins in cell cycle regulation, apoptosis and DNA damage response in cancer and neurodevelopment. Furthermore, through the use of therapeutic agents to up-regulate aquaglyceroporin 9 expression, he is also investigating the possibility of extending the application of arsenic trioxide beyond the treatment of acute promyelocytic leukaemia.