Gabriella Sármay
Associate professor
Immunology
Lorand Laboratories LLC
Hungary
Biography
Dr.Gabriella Sármay is worked at Weizmann Institute of Science in the Department of Chemical Immunology, Israel 1990 during 1991. She worked asa a guest researcher at Vienna International Research Cooperation Center in Sandoz Forschungsinstitute 1992 during 1995.
Research Interest
Dr.Gabriella Sármay main interest is the regulation of the humoral immune response, the “crosstalk” between receptors expressed on B lymphocytes. Binding of antigens and other ligands to the corresponding receptors on B cells stimulates intracellular signalling pathways that interact with each other and construct signalling networks determining the fate of the cell: activation, proliferation, differentiation or cell death. Simultaneously bound ligands induce signals that may collaborate and control B cells’ negative or positive selection, playing crucial role in maintenance of tolerance.
Publications
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In vitro eradication of citrullinated protein specific B-lymphocytes of rheumatoid arthritis patients by targeted bifunctional nanoparticles
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MZ B cells migrate in a T-bet dependent manner and might contribute to the remission of collagen-induced arthritis by the secretion of IL-10.
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Induction and Differentiation of IL-10-Producing Regulatory B Cells from Healthy Blood Donors and Rheumatoid Arthritis Patients
