Jozsef Prechl
Principal Investigator
Immunology
Lorand Laboratories LLC
Hungary
Biography
József Prechl completed his Diploma in general medicine in the 1993 at Semmelweis University Medical School (SE) and his Ph.D Scientific degree in biology in the year 2003 at Eötvös Loránd University (ELTE).His Postdoctoral training/fellowships: Academische Ziekenhuise Utrecht, Holland, COPERNICUS fellowship (1996, 18 month); University of Wisconsin-Madison, USA - Széchenyi fellowship (2003, 1.5 months) visiting scholar (2004, 2005, 2006, 2009) József Prechl awarded as Scientific awards: 1997. Bio-Science award; 1999. Tüdogyógyászati, Allergológiai és Immunológiai Megbetegedések (TAIM) Nemzetközi Alapítvány II. Díja; 2000. Kisfaludy Lajos Fund award, 2003 Academic Youth Award, 2007 Eötvös Research and Education Award
Research Interest
Jozsef Prechl group has been developing protein arrays for the characterization of immune response since 2006. We started our work with handheld array spotters and microscopic detection, by now – in collaboration with Diagnosticum Inc.- we have set up two protein array laboratories. One of these is capable of producing and reading arrays, the other one is for higher throughput serum diagnostic projects. Jozsef Prechl main objective is the development of novel immunological assays for protein microarray platforms. Our unique technology is based on the monitoring of complement activation events on antigen arrays. By multiplex measurements we aim to generate comprehensive data sets that describe antibody initiated events upon antigen binding. Currently we are developing cellular detection methods for the characterization of serum antibodies and microfluidic approaches for the monitoring of antibody-cell interactions.
Publications
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Complementing antibody profiles: assessing antibody function on antigen microarrays
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Immune complex signatures of patients with active and inactive SLE revealed by multiplex protein binding analysis on antigen microarrays
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Application of fluorescent monocytes for probing immune complexes on antigen microarrays