Mihaly Jozsi

Biography

Dr. Mihaly Jozsi completed his M.Sc in biology and English translation in the year 1997 at Eötvös Loránd University, Budapest and his Ph.Din immunology in the year 2002 at  Eötvös Loránd University, Budapest. 2002-2006, postdoctoral researcher at Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie – Hans-Knöll-Institut, Jena, Germany 2006-2012, junior research group leader, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie – Hans-Knöll-Institut, Jena, Germany.scholarships, fellowships: DAAD-scholarship (2001, 5 months), Eötvös Fellowship of the Hungarian State (2002, 6 months), Humboldt Research Fellowship (Alexander-von-Humboldt Stiftung, 2003-2004, 21 months).prizes: BioScience-prize (2003), Medac Forschungspreis (2004, 2007) Dr. Mihaly Jozsi current position: senior research fellow, head of MTA-ELTE „Lendület” Complement Research Group at the Department of Immunology, Eötvös Loránd University

Research Interest

Dr. Mihaly Jozsi research concerns the complement system of innate immunity, particularly the function and regulation of the alternative complement pathway, the structure and function of factor H and factor H-related proteins. Complement is involved in the pathomechanism of several diseases. Dysregulation of the alternative pathway, polymorphisms and mutations in factor H or anti-factor H autoantibodies play a role in various diseases, including age-related macular degeneration (a leading cause of blindness in the Western world) and the kidney diseases atypical hemolytic uremic syndrome and dense deposit disease). Our main aim is to unveil the physiological roles of factor H and factor H-related proteins, in order to understand their role in diseases, which could then lead to tailored treatments in the future. Keywords: innate immunity, complement system, autoimmunity, complement-mediated diseases, factor H protein family, pentraxins