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Dr. Anjali Jha

DST-INSPIRE Faculty
Nanobioscience
Agharkar Research Institute
India

Biography

Her Education & Scientific Career: Postdoctoral: Department of Bioengineering, Stanford University, USA, Ph.D.: Tata Institute of Fundamental Research (TIFR), Mumbai, India. Thesis title: Site-specific dynamics of proteins and protein fibrils revealed by time-domain fluorescence, M.Sc. in Chemistry, Indian Institute of Technology, Roorkee, India and B.Sc. in Chemistry, Nowrosee Wadia College, University of Pune, India.

Research Interest

Protein misfolding & aggregation, amyloid and prion biology, nanoparticles assisted drug delivery agents to target alzheimer disease.

Publications

  • Jha A, Narayan S, Udgaonkar JB, Krishnamoorthy G. Solvent-induced tuning of internal structure in a protein amyloid protofibril. Biophys J. (2012), 103:797-806.

  • Jha A, Ishii K, Udgaonkar JB, Tahara T, Krishnamoorthy G. Exploration of the correlation between solvation dynamics and internal dynamics of a protein. Biochemistry. (2011), 50:397-408.

  • Jha A, Udgaonkar JB, Krishnamoorthy G. Characterization of the heterogeneity and specificity of interpolypeptide interactions in amyloid protofibrils by measurement of site-specific fluorescence anisotropy decay kinetics. J Mol Biol. (2009), 393:735-52. (Featured as the journal cover page article))

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