Dr. Chinmoy Patra
Scientist C
Developmental Biology
Agharkar Research Institute
India
Biography
His Scientific Career: From 2014 : Scientist at the Agharkar Research Institute, Department of Developmental Biology, Pune, INDIA, 2012-2014 : Post-Doctoral work with Prof. Didier Stainier Department of Developmental Genetics, Max-Planck-Institute for Heart and Lung Research, Germany, 2010-2012 : Post-Doctoral work with Prof. Felix B. Engel Department of Heart Development and Regeneration, MPI for Heart and Lung Research, Germany, 2007-2010 : Performed Doctoral thesis work under the guidance of Prof. Felix B. Engel at Max Planck Institute for Heart and Lung Research, Germany, 2005-2007 : Master of Technology (Biotechnology and Biochemical Engineering) from Indian Institute of Technology, Kharagpur, India and Technical University of Dresden, Germany. (Under the DAAD Fellowship offer), 2001-2005 : Bachelor of Pharmaceutical science. Jadavpur University, Kolkata, India.
Research Interest
Development of an organ or new life is a spectacular process, which is controlled by spatiotemporal gene expression. Their lab is interested to understand how extracellular matrix (ECM) molecules and adhesion G-protein coupled receptors are involved in organ development, tissue homeostasis, organ function and regeneration at the cellular level, using zebrafish and mouse as model organisms. They investigate their questions utilizing state-of-the-art technology TALEN and CRISPR-Cas based gene mutagenesis, genome editing, fluorescent reporter lines, transgenesis, and high resolution live imaging. One of our goals is to understand the crosstalk between different cell types via ECM components during cardiac development and vessel formation.
Publications
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Patra C,Ricciardi F, and Engel FB.The functional properties of nephronectin: an adhesion molecule for cardiac tissue engineering. Biomaterials (ISSN#0142-9612)2012;33(17):4327–4335 (IF-8.5).
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Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C and Engel FB. Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain dependent. Proc. Natl. Acad. Sci. USA (ISSN#1091-6490)2013; 110 (42):16898-16903 (IF-10.5).
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Patra C, Boccaccini AR and Engel FB. Vascularization for cardiac tissue engineering: the extracellular matrix. Thrombosis and Haemostasis (ISSN# 1538-7836) 2014; (IF-5.6). Review Article; (In Press)