K. L. Surekha
Scientist
Developmental Biology Group
Agharkar Research Institute
India
Biography
Ph.D, SERB-Young Scientist.Wnt and Bone Morphogenetic Protein (BMP) family members regulate several processes during embryogenesis such as cell proliferation and differentiation, fate specification, dorso-ventral patterning and stem cell maintenance. Involvement of both Wnt/BMP pathways in axis formation and stem cell maintenance has already been reported. Hydra shows lack of senescence with extremely low mortality rate and is often considered as a perpetual embryo. Also, hydra possesses three distinct stem cell lineages and thus could be explored as a powerful stem cell model. We aim to study the molecular interactions and the signaling cross talks between these two pathways to understand the stem cell niche and evolution of body plans using hydra as a model. Her Education and scientific career:SERB-Young scientist, Agharkar Research Institute, Pune, Post-Doctoral research fellow at Agharkar Research Institute, Pune, Ph.D. at Agharkar Research Institute, Pune and M.Sc., University of Hyderabad, Telangana.
Research Interest
Signalling mechanisms underlying Hydra regeneration and pattern formation
Publications
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Krishnapati LS, Ghaskadbi S (2013). Isolation and characterization of VEGF and FGF from Hydra. Int J Dev Biol. 57: 897-906.
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Surekha KL, Waghchoude M, Ghaskadbi S (2013). Enhancement of angiogenesis by a 27 kDa lectin from perivitelline horseshoe crab embryos through up-regulation of VEGF and its receptor. J Nat Prod. 76(1): 117-120.
