Souvik Sen Gupta
Assistant Professor
Division of Biological & Life Sciences
Ahmedabad University, Ahmedabad
India
Biography
Souvik Sen Gupta is an Assistant Professor at Division of Biological & Life Sciences, Ahmedabad University. He did his Bachelors in Physiology from Calcutta University in 2003, Masters in Biotechnology from Calcutta University in 2005 and completed his Ph.D. in Molecular Biology and Biochemistry of the parasite Leishmania in 2011 from Indian Institute of Chemical Biology, Kolkata, India. He moved to University of Aarhus, Denmark for postdoctoral studies and worked in the field of eukaryotic replication with yeast as a model organism. He returned to India in November 2012 and joined the Indian Association for the Cultivation of Science, Kolkata, India as DBT Research Associate where his research was directed towards the identification of a novel DNA repair protein in Leishmania. He also worked as part-time lecturer and guest lecturer at Department of Microbiology, Asutosh College, Kolkata. His doctoral research was based on topoisomerases and cell death of unicellular protozoan parasite Leishmania and he published his research work in peer-reviewed journals. During his postdoctoral tenure in University of Aarhus, Denmark, he gained significant exposure to yeast molecular biology and genetics. Later during his DBT-RA tenure, he worked in the field of Leishmania molecular biology. He also authored a book based on his doctoral research published by LAP Lambert Academic Publisher in 2012.
Research Interest
His research interests are in the field of molecular parasitology, DNA repair and topoisomerase targeted therapeutics.
Publications
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Das BB, Huang SY, Murai J, Rehman I, Amé JC, Sengupta S, Das SK, Majumdar P, Zhang H, Biard D, Majumder HK, Schreiber V, Pommier Y. (2014) PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage. Nucleic Acids Res.; 42(7):4435-49. [IF: 8.808]
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Chowdhury S, Mukhopadhyay R, Saha S, Mishra A, Sengupta S, Roy S, Majumder HK. (2014) Flavone resistant Leishmania donovani over expresses LdMRP2 transporter in the parasite and activates host MRP2 on macrophages to circumvent the flavone-mediated cell death. J Biol Chem.; 289(23):16129-16147. [IF: 4.600]
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Das SK, Rehman I, Ghosh A, Sengupta S, Majumdar P, Jana B, Das BB. (2016) Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells. Nucleic Acids Res.; 44(17):8363-8375. [IF: 8.808]
