Harpal Singh
Professor
Biomedical Engineering
All India Institute of Medical Sciences
India
Biography
Dr. Harpal Singh is an full time Professor at All Indian Institute for Medical Sciences
Research Interest
Drug Delivery Systems, Antimicrobial Polymers for Water Disinfection, Polymer synthesis and modification for Biomedical and Industrial application. Our group is contributing in the research area of biomedical nanotechnology. A major focus is on the ‘Development of polymers to deliver drugs, particularly chemotherapeutic drugs/peptides/DNA, continuously at controlled rate for prolonged period of time. These interdisciplinary research activities are in collaboration with Dana Farber Cancer Institute, Boston, USA; AIIMS, INMAS (DRDO) and NIHFW, Delhi, India.
Publications
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Lomas Tomar, Charu Tyagi, Manoj Kumar, Pradeep Kumar, Harpal Singh, Yahya E Choonara, Viness Pillay. In Vivo evaluation of conjugated poly(lactide-ethylene glycol) nanopartilce depot formulation for prolonged insulin delivery in the diabetic rabbit model. International Journal of Nanomedicine, 2013: 8 5055-520.(IF-4.19)
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Vivek Bansal, Manoj Kumar, Manu Dalela, H.G. Brahmne and Harpal Singh. Evaluation of Synergistic Effect of Biodegradable polymeric Nanoparticles and Aluminum based Adjuvant for Improving Vaccine Efficacy. International Journal of Pharmaceutics, 471 (2014) 377–384.(IF-4.09).
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Anita Mann, Vasundhara Shukla, Richa Khanduri, Spoorti Dabral, Harpal Singh, and Munia Ganguli. Linear Short Histidine and Cysteine Modified Arginine Peptides Constitute a Potential Class of DNA Delivery Agents. Mol. Pharmaceutics, 2014, 11 (3), pp 683–696.(IF-4.78)
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Manoj Kumar, Dikshi Gupta, Gurpal Singh, Sapna Sharma, Madhusudan Bhatt, C.K. Prashant, A.K. Dinda, Surender Kharbanda, Donald Kufe, and Harpal Singh. Novel polymeric nanoparticles for intracellular delivery of peptide cargos: antitumor efficacy of the Bcl-2 conversion peptide NuBCP-9. Cancer Research 2014, 74: 3271-3281. (IF-9.26)
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Manoj Kumar, Gurpal Singh, Sapna Sharma, Dikshi Gupta, Vivek Bansal, Vikas Arora, Madhusudan Bhat, Sandeep K. Srivastava, Sameer Sapra, Surender Kharbanda, Amit K. Dinda and Harpal Singh Intracellular delivery of peptide cargos using iron oxide based nanoparticles: studies on antitumor efficacy of BCL-2 converting peptide, NuBCP-9. Nanoscale, 2014 (IF- 6.74)
