Prasanna Ramani
professor
Chemistry
Amrita University - Amrita Vishwa Vidyapeetham
India
Biography
Dr. Prasanna Ramani did his master’s degree in Chemistry from Bharathidasan University, India and Ph. D. in Chemical Sciences from University of Milan, Italy. His doctoral thesis work was focused on Synthesis/labeling of Modified Peptide Nucleic Acids (artificial DNA) and their Analytical Properties. Dr. Ramani worked on polymer chemistry, total synthesis of natural products and functionalization of CNTs during his tenure as a postdoctoral researcher at Center for bio-molecular Interdisciplinary Studies and Industrial applications (CISI), University of Milan, Italy. His postdoctoral research was supported by UNESCO grant from University of Trieste, Italy. Before his doctoral studies, Dr. Ramani worked for three years as Senior Chemist at Orchid Chemicals and Pharmaceuticals Ltd., Chennai, India. He has organized, participated and presented in various meetings and workshops around India and Europe. Dr. Ramani is also guiding a number of undergraduate & postgraduate student projects and Ph. D. research scholars. He currently researches on synthesis of biologically interesting molecules and natural product chemistry.
Research Interest
He currently researches on synthesis of biologically interesting molecules and natural product chemistry.The research team targets on the synthesis of new molecules that can target cancer. Cancer results from mutation of certain genes that allow the cells to begin their uncontrolled growth. These mutations are inherited or acquired. The group members intend to find a possible solution towards cancer free world. The following are our Research interests: Peptide Nucleic Acids: The remarkable binding properties of ‘Peptide Nucleic Acids’ (PNA), the so called artificial DNAs, have spawned a rapidly expanding new field of research and their applications as therapeutics, DNA diagnostics, tools in biotechnology and much more. PNA is linked to various scientific disciplines, few includes medicinal chemistry, biochemistry, molecular biology, immunology and drug development. Our focus is to improve the solubility and sensitivity to detect complementary natural nucleobases.
Publications
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Dr. Prasanna Ramani, Vijith, V. S., Harikrishnan, K. V., Krishnapriya, S., Varma, V., Jose, A., Kumar, E. P., and P.K., K. Namboori, “Design of Novel Drug Molecules for the Treatment of Breast Cancerâ€, International Journal of Pharmaceutical Sciences Review and Research, 2013.
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K. Silpa, Shilpa, G. S., and Dr. Prasanna Ramani, “Applications of Fluorescent Makersâ€, J. Environ. Nanotechnol, vol. 4, pp. 16–18, 2015.
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Na Thomas, Dr. Subin Mary Zachariah, and Dr. Prasanna Ramani, “4-Aryl-4H-Chromene-3-Carbonitrile Derivates: Synthesis and Preliminary Anti-Breast Cancer Studiesâ€, Journal of Heterocyclic Chemistry, 2015