Kamala K. Vasu
Professor
Medicinal Chemistry
B. V. Patel Pharmaceutical Education & Research Development Centre
India
Biography
Dr. Kamala K. Vasu is Assistant Director, Dean of Student's Affairs and Head Department of Medicinal Chemistry. She has more than 28 years of research experience. She did her master’s and doctorate in Organic Chemistry from Osmania University, Hyderabad. Later she had been to Academia Sinica, Taipei, Taiwan for her Post Doctoral research work.Her research interests are in the design and synthesis of NCEs for specific therapeutic areas like, for cancer, diabetes, Alzheimer's Disease , adenosine receptors and inflammation. Her group has synthesized many novel thiazoles, thiophenes, imidzoles, quinazoline derivatives and screened for their activity. Many of the molecules were as potential NF-kB and AP-1 transcriptional expression inhibitors implicated in autoimmune diseases and cancer and also as adenosine receptor antagonists. She is also working in impurity profiling and synthesis of the impurities and in CADD and established the same in the instituteOutcome of her research has resulted in US and European patents and many international publications in peer review journals. In addition she has also filed for five Indian Patents and more than 55 more publications in peer reviewed journals.She has collaborations with Lousiana State University, USA, Wurzberg University , Germany.She has been teaching both undergraduates and the post graduate students. She has guided sixteen students for their Ph. D thesis and four are presently working. She has guided more than 30 M. Pharm. students for their project work. She has also given summer training to a number students from Gujarat and other states. She has given a number invited lectures both in Gujarat and in other states. She has received many grants from Government and from Industries.
Research Interest
Design and synthesis of New Chemical Entities [NCEs] for specific therapeutic areas like Inflammation, Cancer and Adenosine receptor ligands [Asthma], Alzheimer’s disease and Tuberculosis
Publications
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Development and validation of stability-indicating HPLC method for imidapril and its degradation products using Design of Experiments (DoE) approach
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Characterization of the degradation products of bambuterol using LCMS- QTOF and NMR 00
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Design, synthesis and biological evaluation of novel pyrazolo-pyrimidinones as DPP-IV inhibitors in diabetes Design, synthesis and biological evaluation of novel pyrazolo-pyrimidinones as DPP-IV inhibitors in diabetes