Dr. Syed Musthapa Meeran
Senior Scientist
Biochemistry
Central Food Technological Research Institute
India
Biography
Dr. Syed Musthapa Meeran is currently a Senior Scientist in the department of Biochemistry Central Food Technological Research Institute, India. He completed B. Sc. Biochemistry-University of Madras, Madras, India, M. Sc. Biochemistry-Aligarh Muslim University, Aligarh, India and Ph. D. Biochemistry- CSIR-Indian Institute of Toxicology Research (IITR), Lucknow.
Research Interest
Mainly focus on exploring the epigenetic role of bioactive diets and dietary supplements on cancer prevention and therapy. We investigate the role of different epigenetic modifications such as DNA methylation and histone acetylation as well as histone methylation changes during the processes of carcinogenesis. We also aim to investigate the epigenetic role of traditional spices and other bioactive diets on the onset of life-style associated diseases including cancer.
Publications
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Tripathi S, Singh P, Singh A, Chagtoo M, Khan S, Tiwari S, Agarwal G, Meeran SM, Godbole MM (2016) Zoledronate and Molecular Iodine Cause Synergistic Cell Death in Triple Negative Breast Cancer through Endoplasmic Reticulum Stress of canonical Wnt/ß-catenin signaling axis. Nutr. Cancer. 68(4): 679-88.
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Sinha S, Khan S, Shukla S, Lakra AD, Kumar S, Das G, Maurya R and Meeran SM (2016) Cucurbitacin B inhibits breast cancer metastasis and angiogenesis through VEGF-mediated suppression of FAK/MMP-9 signaling axis. Int. J. Biochem. & Cell Biol. In Press
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Shukla S, Sinha S, Khan S, Kumar S, Singh K, Mitra K, Maurya R and Meeran SM (2016) Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/ß-catenin signaling axis. Sci. Rep. 6: 21860.