Krishnan H Harshan
Senior Scientist
Molecular Biology
Centre for Cellular and Molecular Biology
India
Biography
Krishnan H Harshan is the Senior Scientist in Centre for Cellular and Molecular Biology.
Research Interest
I currently use two different viral systems for studies: HCV is a positively sensed RNA virus which is transmitted across humans through blood. HCV infection could lead to chronic infection in more than 70% of the infected persons, which ultimately results in the development of liver cirrhosis (LC) and hepatocellular carcinoma (HCC).
Publications
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Krishnan, H.H., Walia, N-S., Streblow D.N., Naranatt, P.P and B. Chandran. 2006. Focal Adhesion Kinase (FAK) is critical for Kaposi’s Sarcoma Associated Herpesvirus (KSHV-HHV-8) entry into the target cells. J. Virology. 80. 1167-1180. (Selected in the J.Virology spotlight in the same issue)
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Krishnan, H.H., Walia, N-S., Zeng, L., Gao, S. J and B. Chandran. 2005. Envelope glycoprotein gB of Kaposi’s sarcoma Associated Herpesvirus (KSHV/HHV-8) is essential for egress from infected cells J. Virology. 79. 10952-10967.
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Krishnan, H.H., Naranatt, P.P., Smith, M.S, Zeng, L, Bloomer, C., and B. Chandran. 2004. Concurrent expression of latent and a limited number of lytic genes with immune modulation and anti-apoptotic functions by KSHV/HHV-8 early during infection of primary endothelial and fibroblast cells and subsequent decline of lytic gene expression. J Virology: 78:3601-20.
