Lekha Dinesh Kumar
Principal Scientist
Molecular Biology
Centre for Cellular and Molecular Biology
India
Biography
Lekha Dinesh Kumar is the Principal Scientist in Centre for Cellular and Molecular Biology.
Research Interest
Lekha Dinesh Kumar's laboratory is interested in studying the changes induced, with an emphasis on wnt signal transduction pathway, during the initiation and progression of colon and breast cancer.
Publications
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Rimpi Khurana, Vinod Kumar Verma, Abdul Rawoof, Shrish Tiwari, Rekha A Nair, Ganesh Mahidhara, Mohammed M Idris, Alan R Clarke, Lekha Dinesh Kumar OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer. BMC Bioinformatics 2014, 15:15.
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Bilal Rah1, Reyaz ur Rasool, Debasis Nayak, Syed Khalid Yousuf, Debaraj Mukherjee, Lekha Dinesh Kumar, and Anindya Goswami PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells. Autophagy 11:2, 314-331;
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Amin H, Nayak D, Ur Rasool R, Chakraborty S, Kumar A, Yousuf K, Sharma PR, Ahmed Z, Sharma N, Magotra A, Mukherjee D, Kumar LD, Goswami A. Par-4 dependent modulation of cellular β-catenin by medicinal plant natural product derivative 3-azido Withaferin A. Molecular Carcinogenesis.