M V Jaganadham
Sr. Principal Scientist
Molecular Biology
Centre for Cellular and Molecular Biology
India
Biography
M V Jaganadham is the Sr. Principal Scientist in Centre for Cellular and Molecular Biology.
Research Interest
Membrane vesicles are found in the medium from Gram –ve bacterium during growth. These proteo-lipids are called outer membrane vesicles (OMV). The functions of these vesicles are not very clear. However, some studies revealed that the vesicles perform several biological functions, such as DNA transfer, and protein delivery to eukaryotic or prokaryotic cells. Characterization of these vesicles may facilitate the design of protein, DNA or other drug carriers.
Publications
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Mishra, M N; Nagarajan, T; Sharma, I M; Jagannadham M V and Tripathi, A K. (2008) Mutation in a gene encoding anti-sigma factor in A. brasilense confers tolerance to elevated temperature, anti-bacterial peptide and PEG-200 via carotenoid synthesis. FEMS Micro. Biol Lett. 287:221-229.
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Jagannadham M V (2008) Identification of proteins from membrane preparations by a combination of MALDI TOF-TOF and LC coupled Linear Ion trap MS analysis of an Antarctic bacterium Pseudomonas syringae Lz4W, a strain with unsequenced genome. Electrophoresis. 29:4341-4350.
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Jagannadham M V and Nagaraj R (2008) Detecting the site of phosphorylation in phosphopeptides without loss of phosphate group using MALDI TOF mass spectrometry. Analytical Chemistry Insights. 3:21-29.