P Chandra Shekar
Sr. Scientist
Molecular Biology
Centre for Cellular and Molecular Biology
India
Biography
P Chandra shekar is the Sr. Scientist Centre for Cellular and Molecular Biology
Research Interest
Pluripotent stem cells establish and maintain a state of equilibrium between self-renewal and differentiation. The pluripotent embryonic stem cells exit this equilibrium to differentiate to any cell type of the body.
Publications
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P. Chandra Shekar*, SandeepGoel*, S. DeepaSelvi Rani, D. ParthaSarathi, Jomini Liza Alex, Shashi Singh, and Satish Kumar; K-Casein-deficient mice fail to lactate. Proc. Natl. Acad. Sci. USA.2006,103,8000-8005
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P. Chandra Shekar, Adnan Naim, D ParthaSarathi, Satishkumar.Argonaute 2 deficient embryonic stem cells are retarded in self-renewal and differentiation. 2011 J. Biosci.36 649-657 DOI10.1007/s12038-011-9094-1
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Fidalgo M*, Shekar PC*, Ang YS, Fujiwara Y, Orkin SH, Wang J. Zfp281 functions as a transcriptional repressor for pluripotency of mouse embryonic stem cells.Stem Cells. 2011 Nov; 29 (11): 1705-16. doi: 10.1002/stem.736.