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Rakesh Kumar Mishra

Director
Molecular Biology
Centre for Cellular and Molecular Biology
India

Biography

Obtained M.Sc. (Chemistry) in 1981 and Ph.D. (Organic Chemistry) in 1986 from the University of Allahabad. Research experience: 1986-1988, postdoctoral research non-B DNA conformations and DNA topolgy at Molecular Biophysics Unit, Indian Institute of Science, Bangalore. 1988-1992, worked at Center for Cellular and Molecular Biology, Hyderabad as scientist and studied transcription initiation in prokaryotes, chemical recognition and cleavage of DNA. 1992-1996, antisense oligonucleotide mediated knock down against protozoan parasites at the University of Bordeaux, France and small nucleolar RNAs in Xenopus oocytes to study their role in rRNA maturation at Saint Louis University School of Medicine, USA. 1996 to 2001, Chromatin organization and regulation of homeotic gene complex of Drosophila melanogaster at the University of Geneva, Switzerland. 2001- Joined CCMB and working on: -Comparative and functional genomics of non-coding DNA -Organization and regulation of Hox complexes: the evolutionary logic of anterior-posterior body axis formation in animals -Epigenetic regulation and development Elected fellow of: J.C. Bose Fellowship Indian Academy of Sciences National Academy of Sciences, India Indian National Academy of Sciences Andhra Pradesh Academy of Sciences

Research Interest

Dr. Rakesh Kumar Mishra Our lab is interested in understanding how information is encoded in genomes and expressed in regulated manner during development and its interaction with the environment.

Publications

  • Transcriptional activation by GAGA factor is through its direct interaction with dmTAF3 Vivek S Chopra, Arumugam Srinivasan, Ram P Kumar, Krishnaveni Mishra, Denis Basquin, Mylène Docquier, Carole Seum, Daniel Pauli, Rakesh K Mishra Dev. Biol. 317, 660-670, 2008.

  • Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkit Ramamoorthy Senthilkumar and Rakesh K Mishra BMC Genomics 10, 459, 2009.

  • Repeat performance: how do genome packaging and regulation depend on simple sequence repeats Ram P Kumar, Ramamoorthy Senthilkumar, Vipin Singh and Rakesh K Mishra BioEssays 32, 165-174, 2010.

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