Radha Krishna P
Chief Scientist
Chemical Technology
CSIR-Indian Institute of Chemical Technology
India
Biography
Twenty three years (after Ph.D.) of research experience on the synthesis of enantiomerically pure compounds.Worked on the projects involving researchers from both domestic and overseas pharma/biotech companies.Design and synthesis of New Chemical Entities for New Drug Discovery process.Creativity in problem solving: Identification/Development of novel synthetic routes/ processes for candidate molecules adopting non-patent infringing routes Expertise in diverse areas of organic synthesis: Aromatics, Carbohydrates, Aliphatic chemistry, Asymmetric synthesis (both by ‘chiron’ approach or chiral catalyst assisted), Design and synthesis of fluorescently labeled analogs of Epothilone B and Baccatin derivatives, C-nucleosides etc. To my Credit total are: Ph. D.s: 22-completed (10-working), MS: 14, Publications: 147, US Patents 14, Indian Patents: 2, Book Chapters-3, Reviews-4.
Research Interest
1)Synthesis of Natural Product 2)Carbohydrate Mimetics 3)Asymmetric Baylis-Hillman reaction 4)Synthetic Methodologies 5)Organocatalysis 6)New Drug Discovery
Publications
-
Radha Krishna, P.; Kannan, V.; Sharma G V M. “First diastereoselective intramolecular Baylis-Hillman reaction: An easy access to chiral alpha-methylene-beta-hydroxylactonesâ€, J. Org. Chem. 2004, 68, 6467-6469.
-
Radha Krishna, P.; Rachna Sachwani, Kannan, V. “Double Asymmetric Induction’ as a novel tool for high stereocontrol in Baylis-Hillman reactionâ€, Chem. Commun.; 2004, 2580-2581.