Prof. J. K. Pal
Professor
"Biotechnology and Bioinformatics Institute"
D.Y. Patil Biotechnology & Bioinformatics Institute
India
Biography
"Prof. J. K. Pal is a Professor in the Department of ""Biotechnology and Bioinformatics Institute"" in D.Y. Patil Biotechnology & Bioinformatics Institute, India with research interest of Regulation of initiation of Protein Synthesis by the heme-regulated eukaryotic initiation factor 2-α-kinase during anemia, thalassemia and various other cytoplasmic stresses, namely, heavy metal-toxicity, heat shock, exposure to free radicals and ionizing radiations"
Research Interest
"Regulation of initiation of Protein Synthesis by the heme-regulated eukaryotic initiation factor 2-α-kinase during anemia, thalassemia and various other cytoplasmic stresses, namely, heavy metal-toxicity, heat shock, exposure to free radicals and ionizing radiations. 2. Molecular diagnostics for anemia, thalassemia and lead-poisoning 3. Molecular mechanism of regulation of protein synthesis in Leishmania donovani. 4. Proteasomes and the regulation of melanin biosynthesis in melanoma cells. "
Publications
-
Mittal Smriti PK, Kulkarni Abhijeet P, Mathai Jinumary Chattopadhyay, Samit Pal JK (2014) Dose-dependent differential response of mammalian cells to cytoplasmic stress is mediated through the heme-regulated eIF-2αkinase. Int J Biochem Cell Biol 54: 186-197.
-
Pujari R, Jose J, Bhavnani V, Kumar N, Shastry P, et al. (2016) Tamoxifeninduced cytotoxicity in breast cancer cells is mediated by glucose-regulated protein 78 (GRP78) via AKT (Thr308) regulation. Int J Biochem Cell Biol 77: 57-67.
-
Bhavnani V, Kaviraj S, Savergave L, Singh A, Raghuwanshi AK, et al. (2017) HRI: A stress response eIF2α kinase exhibits structural and functional stability at high temperature and alkaline conditions. Int J Biol Macromol 95: 528-538.
