Nitya Shree

Biography

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits   CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models   3. CNX-012-CPD, a direct AMPK activator provides strong glycemic and lipid control in both in vitro and in vivo animal models   1. A novel HSD11B1 inhibitor provides glycemic and lipid control along with significant reduction in weight in C57BL6/J mice on HFD   2. Safe and selective small molecule RXRa agonist modulates glucose and lipid metabolism in Ob/Ob mice.

Research Interest

stem cell